Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 13289
TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774116(US12428433, Example 3)
Affinity DataIC50: 0.360nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774115( WO2019210835, Example 5 | US12428433, Positive co...)
Affinity DataIC50: 0.390nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774114(US12428433, Example 2)
Affinity DataIC50: 0.420nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774117(WO2019210835, Example 6 | US12428433, Positive con...)
Affinity DataIC50: 0.430nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 0.470nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774120(US12428433, Example 6)
Affinity DataIC50: 0.520nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774109(US12428433, Example 1)
Affinity DataIC50: 0.620nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774115( WO2019210835, Example 5 | US12428433, Positive co...)
Affinity DataIC50: 0.720nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774116(US12428433, Example 3)
Affinity DataIC50: 0.890nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774117(WO2019210835, Example 6 | US12428433, Positive con...)
Affinity DataIC50: 0.970nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774114(US12428433, Example 2)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774117(WO2019210835, Example 6 | US12428433, Positive con...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774116(US12428433, Example 3)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774115( WO2019210835, Example 5 | US12428433, Positive co...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774114(US12428433, Example 2)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774109(US12428433, Example 1)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774120(US12428433, Example 6)
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774109(US12428433, Example 1)
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774120(US12428433, Example 6)
Affinity DataIC50: 8.20nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774119(US12428433, Example 5)
Affinity DataIC50: 127nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774118(US12428433, Example 4)
Affinity DataIC50: 320nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774119(US12428433, Example 5)
Affinity DataIC50: 561nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774118(US12428433, Example 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774119(US12428433, Example 5)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical Co.

US Patent
LigandPNGBDBM774118(US12428433, Example 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activities of the compound of the present application on three kinases TRKa, TRKA(G595R) and TRKC(G623R) were measured.2. Experimental Mat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent