Compile Data Set for Download or QSAR
Report error Found 386 Enz. Inhib. hit(s) with all data for entry = 13412
TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787709BDBM787709(US12473295, Compound 177)
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787788BDBM787788(US12473295, Compound 356)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787673BDBM787673(US12473295, Compound 94)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787624BDBM787624((R)-N-ethyl-5-fluoro-N-isopropyl-2-((5-(2-(2-methy...)
Affinity DataIC50: 8.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787680BDBM787680(US12473295, Compound 112)
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787790BDBM787790(US12473295, Compound 365)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787764BDBM787764(US12473295, Compound 283)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787778BDBM787778(US12473295, Compound 334)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787695BDBM787695(US12473295, Compound 150)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787707BDBM787707(US12473295, Compound 172)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787776BDBM787776(US12473295, Compound 325)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787686BDBM787686(US12473295, Compound 132)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 788822BDBM788822(US12473295, Compound 104)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787659BDBM787659(N-ethyl-5-fluoro-N-isopropyl-2-((5-(2-(6-((2-metho...)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787688BDBM787688(US12473295, Compound 135)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787708BDBM787708(US12473295, Compound 176)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787805BDBM787805(US12473295, Compound 396)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787711BDBM787711(US12473295, Compound 181)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787699BDBM787699(US12473295, Compound 159)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689587BDBM689587(US20240261292, Compound A | US20240261292, Compoun...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787808BDBM787808(US12473295, Compound 402)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689587BDBM689587(US20240261292, Compound A | US20240261292, Compoun...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787704BDBM787704(US12473295, Compound 167)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787650BDBM787650(US12473295, Compound 40)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787701BDBM787701(US12473295, Compound 162)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787745BDBM787745(US12473295, Compound 251)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787737BDBM787737(US12473295, Compound 233)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787715BDBM787715(US12473295, Compound 189)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787702BDBM787702(US12473295, Compound 163)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787561BDBM787561((R)-2-((5-(2-(6-(dimethylamino)-2-methylhexan-3-yl...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787791BDBM787791(US12473295, Compound 366)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787692BDBM787692(US12473295, Compound 145)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787681BDBM787681(US12473295, Compound 114)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787698BDBM787698(US12473295, Compound 157)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787703BDBM787703(US12473295, Compound 165)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787651BDBM787651(US12473295, Compound 41)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787689BDBM787689(US12473295, Compound 137)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787675BDBM787675(US12473295, Compound 99)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787749BDBM787749(US12473295, Compound 258)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787710BDBM787710(US12473295, Compound 179)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787697BDBM787697(US12473295, Compound 154)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787690BDBM787690(US12473295, Compound 140)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787768BDBM787768(US12473295, Compound 300)
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787784BDBM787784(US12473295, Compound 346)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787677BDBM787677((*R)-2-((5(2-(6-(dimethylamino)-2-methylhexan-3-yl...)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetMenin(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787809BDBM787809((R)-2-((5-(2-(6-amino-2-methylhexan-3-yl)-2,6-diaz...)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 787629BDBM787629((R)-N-ethyl-5-fluoro-N-isopropyl-2-((5-(2-(2-methy...)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

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