Compile Data Set for Download or QSAR
Report error Found 124 Enz. Inhib. hit(s) with all data for entry = 13494
TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799269BDBM799269((2S)-1-hydroxy-2-((S)-4-methyl-2-((((4-(trifluorom...)
Affinity DataIC50: 50nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799290BDBM799290((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4S)-4-phe...)
Affinity DataIC50: 70nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 70nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799333BDBM799333((2S)-1-hydroxy-2-((S)-4-methyl-2-((((perfluorophen...)
Affinity DataIC50: 70nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50662446BDBM50662446(CHEMBL6175844 | US12583820, Compound 6g)
Affinity DataIC50: 70nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 509973BDBM509973(Advanced SARS-CoV-2 Inhibitor 6j | acs.jmedchem.1c...)
Affinity DataIC50: 80nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799293BDBM799293(5-ethyl-1,3-dioxan-5-yl ((S)-1-(((S)-1-hydroxy-3-(...)
Affinity DataIC50: 80nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799274BDBM799274((2S)-2-((S)-2-((((4,4-difluorocyclohexyl)oxy)carbo...)
Affinity DataIC50: 80nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799327BDBM799327((2S)-2-((S)-2-((((3-fluorobenzyl)oxy)carbonyl)amin...)
Affinity DataIC50: 80nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799299BDBM799299((2S)-2-((S)-2-((((4,4-dimethylcyclohexyl)oxy)carbo...)
Affinity DataIC50: 90nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799320BDBM799320((4,4-Difluorocyclohexyl)(phenyl)methyl ((S)-4-meth...)
Affinity DataIC50: 100nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50662444BDBM50662444(CHEMBL5085894 | US12583820, Compound 10c)
Affinity DataIC50: 100nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799270BDBM799270((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4S)-4-(tr...)
Affinity DataIC50: 100nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799307BDBM799307((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4R)-4-pro...)
Affinity DataIC50: 110nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799315BDBM799315((2S)-2-((2S)-2-(((1-(4,4-difluorocyclohexyl)ethoxy...)
Affinity DataIC50: 120nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50662446BDBM50662446(CHEMBL6175844 | US12583820, Compound 6g)
Affinity DataIC50: 120nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799272BDBM799272((2S)-2-((S)-2-((((4-butylcyclohexyl)oxy)carbonyl)a...)
Affinity DataIC50: 130nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799337BDBM799337((2S)-1-hydroxy-2-((2S)-4-methyl-2-(((1-phenylbutox...)
Affinity DataIC50: 130nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799336BDBM799336(1-Phenylbutyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-...)
Affinity DataIC50: 150nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799269BDBM799269((2S)-1-hydroxy-2-((S)-4-methyl-2-((((4-(trifluorom...)
Affinity DataIC50: 150nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799305BDBM799305((2S)-2-((S)-2-(((((1s,4S)-4-butylcyclohexyl)oxy)ca...)
Affinity DataIC50: 150nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 509972BDBM509972(Advanced SARS-CoV-2 Inhibitor 6e | acs.jmedchem.1c...)
Affinity DataIC50: 150nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799322BDBM799322(1-(4,4-Difluorocyclohexyl)pentyl ((S)-4-methyl-1-o...)
Affinity DataIC50: 160nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799321BDBM799321((2S)-2-((2S)-2-((((4,4-difluorocyclohexyl)(phenyl)...)
Affinity DataIC50: 160nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799319BDBM799319((2S)-2-((2S)-2-(((1-(4,4-difluorocyclohexyl)-2-phe...)
Affinity DataIC50: 160nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799285BDBM799285((2S)-2-((S)-2-((((5-ethyl-1,3-dioxan-5-yl)oxy)carb...)
Affinity DataIC50: 160nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799304BDBM799304((1s,4S)-4-Butylcyclohexyl ((S)-4-methyl-1-oxo-1-((...)
Affinity DataIC50: 160nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799337BDBM799337((2S)-1-hydroxy-2-((2S)-4-methyl-2-(((1-phenylbutox...)
Affinity DataIC50: 180nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799305BDBM799305((2S)-2-((S)-2-(((((1s,4S)-4-butylcyclohexyl)oxy)ca...)
Affinity DataIC50: 180nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799279BDBM799279(((1r,4S)-4-(Trifluoromethyl)cyclohexyl)methyl ((2S...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799278BDBM799278((4-(Trifluoromethyl)cyclohexyl)methyl ((2S)-4-meth...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799297BDBM799297((1r,4S)-4-Phenylcyclohexyl ((S)-4-methyl-1-oxo-1-(...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799285BDBM799285((2S)-2-((S)-2-((((5-ethyl-1,3-dioxan-5-yl)oxy)carb...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799315BDBM799315((2S)-2-((2S)-2-(((1-(4,4-difluorocyclohexyl)ethoxy...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799303BDBM799303((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1s,4S)-4-pro...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799269BDBM799269((2S)-1-hydroxy-2-((S)-4-methyl-2-((((4-(trifluorom...)
Affinity DataIC50: 210nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799269BDBM799269((2S)-1-hydroxy-2-((S)-4-methyl-2-((((4-(trifluorom...)
Affinity DataIC50: 210nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799307BDBM799307((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4R)-4-pro...)
Affinity DataIC50: 210nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799314BDBM799314(1-(4,4-Difluorocyclohexyl)ethyl ((S)-4-methyl-1-ox...)
Affinity DataIC50: 210nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799319BDBM799319((2S)-2-((2S)-2-(((1-(4,4-difluorocyclohexyl)-2-phe...)
Affinity DataIC50: 220nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799306BDBM799306(((1r,4R)-4-Propylcyclohexyl)methyl ((2S)-4-methyl-...)
Affinity DataIC50: 220nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799270BDBM799270((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4S)-4-(tr...)
Affinity DataIC50: 220nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799318BDBM799318(1-(4,4-Difluorocyclohexyl)-2-phenylethyl ((S)-4-me...)
Affinity DataIC50: 230nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799301BDBM799301((2S)-1-hydroxy-2-((S)-2-(((((1r,4S)-4-isopropylcyc...)
Affinity DataIC50: 230nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799299BDBM799299((2S)-2-((S)-2-((((4,4-dimethylcyclohexyl)oxy)carbo...)
Affinity DataIC50: 240nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799290BDBM799290((2S)-1-hydroxy-2-((S)-4-methyl-2-(((((1r,4S)-4-phe...)
Affinity DataIC50: 250nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799323BDBM799323((2S)-2-((2S)-2-((((1-(4,4-difluorocyclohexyl)penty...)
Affinity DataIC50: 250nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799300BDBM799300((1r,4S)-4-isopropylcyclohexyl ((S)-4-methyl-1-oxo-...)
Affinity DataIC50: 250nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799302BDBM799302((1s,4S)-4-propylcyclohexyl ((S)-4-methyl-1-oxo-1-(...)
Affinity DataIC50: 260nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799298BDBM799298(4,4-Dimethylcyclohexyl ((S)-4-methyl-1-oxo-1-(((S)...)
Affinity DataIC50: 280nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

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