Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 12368
TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50634158BDBM50634158(CHEMBL5402615 | US12599616, Example 2)
Affinity DataIC50: 3.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50634156BDBM50634156(CHEMBL5433446 | US12599616, Example 38)
Affinity DataIC50: 3.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624913BDBM624913(tert-butyl (E)-(4-(N'-cyano-N-((1,2,3,5,6,7-hexahy...)
Affinity DataIC50: 3.80nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 487370BDBM487370((E)-3-(dimethylamino)-N-((1,2,3,5,6,7-hexahydro-s-...)
Affinity DataIC50: 5.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624837BDBM624837((E)-3-(cyclobutyl(methyl)amino)-N-((1,2,3,5,6,7-he...)
Affinity DataIC50: 6nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624954BDBM624954((E)-N'-cyano-3-(dimethylamino)-N-((1,2,3,5,6,7-hex...)
Affinity DataIC50: 6.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 487395BDBM487395((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 6.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624842BDBM624842((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 7.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624864BDBM624864((E)-3-(dimethylamino)-N-((1,2,3,7-tetrahydro-s-ind...)
Affinity DataIC50: 9.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 577199BDBM577199((E)-3-(ethyl(methyl)amino)-N-((1,2,3,5,6,7-hexahyd...)
Affinity DataIC50: 9.90nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624863BDBM624863((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 11nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624952BDBM624952((E)-3-amino-N'-cyano-N-((1,2,3,5,6,7-hexahydro-s-i...)
Affinity DataIC50: 12nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 624899BDBM624899((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 12.6nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 487369BDBM487369((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 487358BDBM487358((E)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carba...)
Affinity DataIC50: 43nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent