Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 13537
TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801928BDBM801928(2-(difluoromethoxy)-N- [(1R,2S)-2- fluorocycloprop...)
Affinity DataIC50: 5.00nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 794657BDBM794657(8-methoxy-6-[6-(2-morpholinoethoxy)pyrazolo[1,5-a]...)
Affinity DataIC50: 5.00nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 794657BDBM794657(8-methoxy-6-[6-(2-morpholinoethoxy)pyrazolo[1,5-a]...)
Affinity DataIC50: 5.00nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801930BDBM801930(8-methoxy-6-[6-(2- morpholinoethoxy) pyrazolo[1,5-...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801930BDBM801930(8-methoxy-6-[6-(2- morpholinoethoxy) pyrazolo[1,5-...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801929BDBM801929(2-(difluoromethoxy)-4- [6-(1,1-dimethyl-2- morphol...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801932BDBM801932(2-(difluoromethoxy)-4- [6-[1,1-dimethyl-2-(2- oxa-...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801931BDBM801931(8-methoxy-6-[7-(2- morpholinoethoxy) imidazo[1,2-b...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801931BDBM801931(8-methoxy-6-[7-(2- morpholinoethoxy) imidazo[1,2-b...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801932BDBM801932(2-(difluoromethoxy)-4- [6-[1,1-dimethyl-2-(2- oxa-...)
Affinity DataIC50: 55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801929BDBM801929(2-(difluoromethoxy)-4- [6-(1,1-dimethyl-2- morphol...)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801928BDBM801928(2-(difluoromethoxy)-N- [(1R,2S)-2- fluorocycloprop...)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 794657BDBM794657(8-methoxy-6-[6-(2-morpholinoethoxy)pyrazolo[1,5-a]...)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801930BDBM801930(8-methoxy-6-[6-(2- morpholinoethoxy) pyrazolo[1,5-...)
Affinity DataIC50: 500nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801931BDBM801931(8-methoxy-6-[7-(2- morpholinoethoxy) imidazo[1,2-b...)
Affinity DataIC50: 500nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801929BDBM801929(2-(difluoromethoxy)-4- [6-(1,1-dimethyl-2- morphol...)
Affinity DataIC50: 500nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801928BDBM801928(2-(difluoromethoxy)-N- [(1R,2S)-2- fluorocycloprop...)
Affinity DataIC50: 500nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Onco3R Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801932BDBM801932(2-(difluoromethoxy)-4- [6-[1,1-dimethyl-2-(2- oxa-...)
Affinity DataIC50: 500nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent