Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 12944
TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808946BDBM808946([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 0.740nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808894BDBM808894([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 1.95nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808943BDBM808943([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 3.08nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808920BDBM808920(US12637454, Example 31)
Affinity DataIC50: 3.72nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808892BDBM808892([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 4.31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808890BDBM808890(US12637454, Example 1)
Affinity DataIC50: 4.48nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808929BDBM808929([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 6.91nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808918BDBM808918(tert-butyl N-[4-[(E)-2-[3-R7R,9aR)-7- | US12637454...)
Affinity DataIC50: 7.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808944BDBM808944([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 9.04nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808905BDBM808905([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 10.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808916BDBM808916([(7R,9aR)-7-(4-chlorophenyl)- | US12637454, Exampl...)
Affinity DataIC50: 10.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808940BDBM808940([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 10.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808948BDBM808948([(7S,9aR)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 11.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808909BDBM808909([(7R,9aR)-7-hydroxy-7-[5- | US12637454, Example 20)
Affinity DataIC50: 11.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808953BDBM808953([7R,9aR)-7-hydroxy-7-[5- | US12637454, Example 64)
Affinity DataIC50: 13.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808950BDBM808950([(7S,9aR)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808947BDBM808947([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 14.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808956BDBM808956(US12637454, Example 67)
Affinity DataIC50: 14.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808933BDBM808933([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 15.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808898BDBM808898([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 16.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808895BDBM808895([(7R,9aS)-7-(4-chloropheny1)-7- | US12637454, Exam...)
Affinity DataIC50: 17.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808919BDBM808919(US12637454, Example 30)
Affinity DataIC50: 18.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808891BDBM808891([(7R,9aS)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 18.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808951BDBM808951([(7S,9aR)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 20.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808932BDBM808932([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 20.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808945BDBM808945([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 37.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808928BDBM808928([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 38.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808952BDBM808952([(7S,9aR)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 39.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808936BDBM808936([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 41.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808899BDBM808899([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 58.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808934BDBM808934([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 66.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808954BDBM808954(US12637454, Example 65)
Affinity DataIC50: 68.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808939BDBM808939([2-chloro-3-(3-hydroxy-3- | US12637454, Example 50)
Affinity DataIC50: 72.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808921BDBM808921([(7R,9aR)-7-hydroxy-7-[5- | US12637454, Example 32)
Affinity DataIC50: 72.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808925BDBM808925([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808893BDBM808893([(7R,9aS)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 76.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808942BDBM808942([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 79.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808938BDBM808938([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 80.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808957BDBM808957(US12637454, Example 68)
Affinity DataIC50: 82.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808941BDBM808941([(7S,9aR)-7-(3-chloro-4-fluorophenyl)- | US1263745...)
Affinity DataIC50: 84.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808924BDBM808924(4-[3-[(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454,...)
Affinity DataIC50: 86nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808907BDBM808907([(7R,9aR)-7-hydroxy-7-[5- | US12637454, Example 18)
Affinity DataIC50: 97.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808949BDBM808949([(7R,9aS)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 118nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808958BDBM808958(US12637454, Example 69)
Affinity DataIC50: 126nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808923BDBM808923(4-(3-((7S,9aR)-7-(4-chlorophenyl)-7- | US12637454,...)
Affinity DataIC50: 145nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808908BDBM808908([(7S,9aS)-7-hydroxy-7-[5- | US12637454, Example 19)
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808922BDBM808922([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 158nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808904BDBM808904([(7S,9aR)-7-(4-chlorophenyl)-7- | US12637454, Exam...)
Affinity DataIC50: 168nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808917BDBM808917([(7R,9aR)-7-(4-chlorophenyl)- | US12637454, Exampl...)
Affinity DataIC50: 169nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808955BDBM808955(US12637454, Example 66)
Affinity DataIC50: 172nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent

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