Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 11538
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624858BDBM624858(US20230322721, Example 5)
Affinity DataIC50: 1.30nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624865BDBM624865(US20230322721, Example 23)
Affinity DataIC50: 1.30nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624852BDBM624852(US20230322721, Example 2)
Affinity DataIC50: 1.5nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624857BDBM624857(US20230322721, Example 4)
Affinity DataIC50: 1.60nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624872BDBM624872(US20230322721, Example 27 | 1-oxide)
Affinity DataIC50: 1.70nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 50579974BDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: 1.80nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624876BDBM624876(US20230322721, Example 29)
Affinity DataIC50: 1.80nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624866BDBM624866(US20230322721, Example 24)
Affinity DataIC50: 1.80nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624862BDBM624862(US20230322721, Example 22)
Affinity DataIC50: 2.10nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624869BDBM624869(US20230322721, Example 26)
Affinity DataIC50: 2.60nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624875BDBM624875(US20230322721, Example 28)
Affinity DataIC50: 3.5nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624860BDBM624860(US20230322721, Example 20)
Affinity DataIC50: 7.20nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624861BDBM624861(US20230322721, Example 21)
Affinity DataIC50: 12.5nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624851BDBM624851(US20230322721, Example 1)
Affinity DataIC50: 36nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624856BDBM624856(US20230322721, Example 3)
Affinity DataIC50: 71nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 624867BDBM624867(US20230322721, Example 25)
Affinity DataIC50: 978nMAssay Description:Each compound was dissolved in DMSO to a concentration of 10 mM and further diluted to 100 μM using acetonitrile. Liver microsomes from selected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent