Compile Data Set for Download or QSAR
Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 11539
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataIC50: 0.0140nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624955(US20230322745, Compound 25)
Affinity DataIC50: 0.0300nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624859(US20230322745, Compound 1 | US20250230148, Compoun...)
Affinity DataIC50: 0.0620nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624956(US20230322745, Compound 28)
Affinity DataIC50: 0.0830nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.104nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.130nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624956(US20230322745, Compound 28)
Affinity DataIC50: 0.136nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624957(US20230322745, Compound 29)
Affinity DataIC50: 0.146nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624960(US20230322745, Compound 33)
Affinity DataIC50: 0.153nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624955(US20230322745, Compound 25)
Affinity DataIC50: 0.179nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.198nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624969(US20230322745, Compound 41)
Affinity DataIC50: 0.201nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624962(US20230322745, Compound 35)
Affinity DataIC50: 0.213nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataIC50: 0.220nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624967(US20230322745, Compound 40)
Affinity DataIC50: 0.228nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624946(US20230322745, Compound 13)
Affinity DataIC50: 0.240nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624961(US20230322745, Compound 34)
Affinity DataIC50: 0.248nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.255nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624969(US20230322745, Compound 41)
Affinity DataIC50: 0.268nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624950(US20230322745, Compound 19)
Affinity DataIC50: 0.281nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624957(US20230322745, Compound 29)
Affinity DataIC50: 0.324nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624878(US20230322745, Compound 4)
Affinity DataIC50: 0.343nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624877(US20230322745, Compound 2)
Affinity DataIC50: 0.347nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624967(US20230322745, Compound 40)
Affinity DataIC50: 0.363nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624947(US20230322745, Compound 14)
Affinity DataIC50: 0.375nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624859(US20230322745, Compound 1 | US20250230148, Compoun...)
Affinity DataIC50: 0.384nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624955(US20230322745, Compound 25)
Affinity DataEC50:  0.388nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624961(US20230322745, Compound 34)
Affinity DataEC50:  0.405nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624960(US20230322745, Compound 33)
Affinity DataIC50: 0.494nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624966(US20230322745, Compound 39)
Affinity DataIC50: 0.533nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624965(US20230322745, Compound 38)
Affinity DataIC50: 0.555nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624962(US20230322745, Compound 35)
Affinity DataIC50: 0.588nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624908(US20230322745, Compound 6)
Affinity DataEC50:  0.624nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624944(US20230322745, Compound 11)
Affinity DataIC50: 0.638nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624977(US20230322745, Compound 31)
Affinity DataIC50: 0.655nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624961(US20230322745, Compound 34)
Affinity DataIC50: 0.657nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624947(US20230322745, Compound 14)
Affinity DataIC50: 0.661nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624962(US20230322745, Compound 35)
Affinity DataEC50:  0.671nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624946(US20230322745, Compound 13)
Affinity DataIC50: 0.687nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624960(US20230322745, Compound 33)
Affinity DataEC50:  0.742nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624963(US20230322745, Compound 36)
Affinity DataIC50: 0.792nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624959(US20230322745, Compound 32)
Affinity DataIC50: 0.814nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624965(US20230322745, Compound 38)
Affinity DataIC50: 0.842nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624964(US20230322745, Compound 37)
Affinity DataIC50: 0.871nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624877(US20230322745, Compound 2)
Affinity DataEC50:  0.889nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624958(US20230322745, Compound 30)
Affinity DataIC50: 1.10nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624973(US20230322745, Compound 3)
Affinity DataIC50: 1.11nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624944(US20230322745, Compound 11)
Affinity DataEC50:  1.12nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624959(US20230322745, Compound 32)
Affinity DataIC50: 1.20nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624966(US20230322745, Compound 39)
Affinity DataIC50: 1.25nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

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