Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 11546
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625585(US20230322792, Example I-9 | (1S,3R)-[3-[4- [pyraz...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625587(US20230322792, Example I-11 | (1S, 3S)-[3-[4- [pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625588(US20230322792, Example I-12 | (1S, 3S)-[3-[4-[3- m...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625582(US20230322792, Example I-6 | trans-5-[2-(3- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625579(US20230322792, Example I-3 | trans-N1-[4-[(3- isop...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625580(US20230322792, Example I-4 | trans-5-[2-(3- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625590(US20230322792, Example I-14 | (1S,3S)-[3-[4-[3- is...)
Affinity DataIC50: 1.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625586(US20230322792, Example I-10 | trans-N1-[4- [pyrazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625581(US20230322792, Example I-5 | trans-5-[2-(3- hydrox...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625583(US20230322792, Example I-7 | trans-5-[2-(3- hydrox...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625584(US20230322792, Example I-8 | trans-5-[2- (piperidi...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625577(US20230322792, Example I-1 | trans-N1-[4-[(3- cycl...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625578(US20230322792, Example I-2 | trans-N1-[4-[(3- cycl...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625589(US20230322792, Example I-13 | (1S,3S)-[3-[4-[2- me...)
Affinity DataIC50: 7.50E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent