Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 11568
LigandPNGBDBM627516(N-(4-(4-amino-7-((1S,4r)-4-(((S)-2-fluoropropyl)am...)
Affinity DataIC50: 1.32nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627508(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 1.60nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627514(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 1.90nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627513(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 2.10nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627509(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 2.10nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627510(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 2.10nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627515(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 2.30nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627502(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 2.70nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627505(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 2.80nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627506(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 3.10nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627508(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 3.30nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627504(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 3.40nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627510(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 3.40nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627515(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 3.5nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627511(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 3.60nMAssay Description:The RNase reactions were performed in 384 well black ProxiPlate-384 Plus plates (PERKIN Elmer) using 50 mM Tris assay buffer with 0.5 mM MgCl2, 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627503(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 4.80nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627513(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 4.80nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627509(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 4.80nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627514(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-morpholinoc...)
Affinity DataIC50: 6nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627511(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-methoxy...)
Affinity DataIC50: 15.5nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627507(N-(4-(4-amino-1-isopropyl-7-((1r,4r)-4-((2-(triflu...)
Affinity DataIC50: 17.9nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

LigandPNGBDBM627512(N-(4-(4-amino-1-isopropyl-7-((1s,4s)-4-morpholinoc...)
Affinity DataIC50: 466nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent