Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 11636
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635742(US20230364079, Example 145)
Affinity DataIC50: 1.69nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM471617(US10822334, Compound ONT380 | US20230382923, Compo...)
Affinity DataIC50: 3nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635746(US20230364079, Example 146)
Affinity DataIC50: 3.92nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635743(US20230364079, Example 152)
Affinity DataIC50: 4.19nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635715(US20230364079, Example 130)
Affinity DataIC50: 4.35nMAssay Description:1) 1× kinase reaction buffer was prepared from 1 volume of 5× kinase reaction buffer and 4 volumes of water, 1 mM dithiothreitol, 5 mM magnesium chlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635693(US20230364079, Example 119)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635561(US20230364079, Example 2-A-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635561(US20230364079, Example 2-A-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635699(US20230364079, Example 122)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635685(US20230364079, Example 115)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635691(US20230364079, Example 118)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635691(US20230364079, Example 118)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635687(US20230364079, Example 116)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635689(US20230364079, Example 117)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635596(US20230364079, Example 8)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635598(US20230364079, Example 9)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635596(US20230364079, Example 8)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635618(US20230364079, Example 12)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635618(US20230364079, Example 12)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635621(US20230364079, Example 13)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635612(US20230364079, Example 10)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635614(US20230364079, Example 11)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635711(US20230364079, Example 128)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635705(US20230364079, Example 125)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635586(US20230364079, Example 6)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635586(US20230364079, Example 6)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635583(US20230364079, Example 5 | US20230364079, Example ...)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635637(US20230364079, Example 92)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635649(US20230364079, Example 98)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635644(US20230364079, Example 24)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635628(US20230364079, Example 16)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635736(US20230364079, Example 111-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635624(US20230364079, Example 14)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635736(US20230364079, Example 111-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635633(US20230364079, Example 89-P2)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635631(US20230364079, Example 89-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635631(US20230364079, Example 89-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635670(US20230364079, Example 37)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635671(US20230364079, Example 109-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635665(US20230364079, Example 106)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635665(US20230364079, Example 106)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635675(US20230364079, Example 110)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635677(US20230364079, Example 111)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635677(US20230364079, Example 111)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM635671(US20230364079, Example 109-P1)
Affinity DataIC50: 5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

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