Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11657
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 14.4nMAssay Description:1. ELISA Assay: The enzyme reaction substrate poly(Glu, Tyr)4:1 was diluted to 20 μg/mL with potassium-free PBS (10 mM sodium phosphate buffer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM375796(US9914707, I-21 | US20230382871, Compound I)
Affinity DataIC50: 19.3nMAssay Description:1. ELISA Assay: The enzyme reaction substrate poly(Glu, Tyr)4:1 was diluted to 20 μg/mL with potassium-free PBS (10 mM sodium phosphate buffer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 30nMAssay Description:1. ELISA Assay: The enzyme reaction substrate poly(Glu, Tyr)4:1 was diluted to 20 μg/mL with potassium-free PBS (10 mM sodium phosphate buffer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM375796(US9914707, I-21 | US20230382871, Compound I)
Affinity DataIC50: 93nMAssay Description:1. ELISA Assay: The enzyme reaction substrate poly(Glu, Tyr)4:1 was diluted to 20 μg/mL with potassium-free PBS (10 mM sodium phosphate buffer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent