Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 11679
TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639154BDBM639154(US20230391736, Example S-217622 | US20250025459, C...)
Affinity DataIC50: 33nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 496902BDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 47nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639156BDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 120nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639158BDBM639158((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 160nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639157BDBM639157(E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-methy...)
Affinity DataIC50: 184nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639157BDBM639157(E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-methy...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639158BDBM639158((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639156BDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639171BDBM639171((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639156BDBM639156(US20230391736, Example 16 | US20230391736, Example...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639167BDBM639167((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639176BDBM639176(US20230391736, Example 21)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639162BDBM639162((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639177BDBM639177((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639163BDBM639163((E)-3-((1H-tetrazol-5-yl)methyl)-1-(4-bromophenyl)...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639173BDBM639173((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639174BDBM639174((E)-6-(2-methyl-2H-indazol-5-yl)imino)-3-(1-ethyl-...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639175BDBM639175((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 375nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639168BDBM639168((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639178BDBM639178((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639165BDBM639165((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639159BDBM639159((E)-3-((1H-tetrazol-5-yl)methyl)-1-benzyl-6-((6-ch...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639160BDBM639160((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639161BDBM639161((E)-3-(1H-tetrazol-5-yl)methyl)-1-(4-(t-butyl)benz...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639169BDBM639169((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639170BDBM639170((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639166BDBM639166((E)-3-(1H-tetrazol-5-yl)methyl)-6-(6-chloro-2-meth...)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639164BDBM639164((E)-3-((1H-tetrazol-5-yl)methyl)-1-([1,1-biphenyl]...)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shaanxi Panlong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 639179BDBM639179((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined by fluorescence resonance energy transfer technique. A suitable amo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent