Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 11684
LigandPNGBDBM639425(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)[(2-...)
Affinity DataIC50: 6nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639431(3-{1-[(6-{[({3- fluorobicyclo[1.1.1] pentan-1- yl}...)
Affinity DataIC50: 6nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639432(({3- fluorobicyclo[1.1.1] pentan-1-yl}methyl) ({[2...)
Affinity DataIC50: 6nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639408(({bicyclo[1.1.1]pentan- 1-yl}methyl)({2-[(4- {6- m...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639410(2-({2-[(4-{6- methoxyimidazo[1,5- a]pyridin-8-yl}-...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639403((cyclobutylmethyl)({2- [(4-{imidazo[1,5- a]pyridin...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639404(({2-[(4-{6- chloroimidazo[1,5- a]pyridin-8-yl}-1H-...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639406(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)({2-...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639399(N-[(6-{[({3- fluorobicyclo[1.1.1] pentan-1- yl}met...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639402(US20230391770, Example 22)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639409(2-({2-[(4- {imidazo[1,5- a]pyridin-8-yl}-1H- 1,2,3...)
Affinity DataIC50: 6.5nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639424(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)[(2-...)
Affinity DataIC50: 8nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639414(US20230391770, Example 34)
Affinity DataIC50: 9.34nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639417(3-{1-[(6- {[({bicyclo[1.1.1] pentan-1- yl}methyl)a...)
Affinity DataIC50: 11.2nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639427(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)[(2-...)
Affinity DataIC50: 13nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639398(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 14.1nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639394(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 14.5nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639405((cyclobutylmethyl)({2- [(4-{1- fluoroimidazo[1,5- ...)
Affinity DataIC50: 15.8nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639421(3-{1-[(6-{[({3- fluorobicyclo[1.1.1] pentan-1-yl} ...)
Affinity DataIC50: 16nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639413(US20230391770, Example 33)
Affinity DataIC50: 18.5nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639395(N-{[6-({[(3,3- difluorocyclobutyl) methyl]amino} m...)
Affinity DataIC50: 27.3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639415(US20230391770, Example 35)
Affinity DataIC50: 27.9nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639391(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 36.5nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639419(3-[1-({6-[(4,4- dimethylpiperidin-1- yl)methyl]imi...)
Affinity DataIC50: 39nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639418(3-{1-[(6- {[(cyclobutylmethyl) amino]methyl} imida...)
Affinity DataIC50: 57nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639426(N-[(6- {[(cyclobutylmethyl) amino]methyl}imidazo [...)
Affinity DataIC50: 74nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639411(US20230391770, Example 31)
Affinity DataIC50: 74.2nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639420(3-(1-{[6-({6- azaspiro[3.4]octan- 6-yl}methyl)imid...)
Affinity DataIC50: 76nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639429(3-{1-[(6-{[({3- fluorobicyclo[1.1.1] pentan-1- yl}...)
Affinity DataIC50: 85nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639387(N-[(6- {[(cyclohexylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 87.7nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639392(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 104nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639416(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)({2-...)
Affinity DataIC50: 105nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639388(N-[(6- {[(cyclohexylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 151nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639423(5-fluoro-3-{1-[(6- {[({3- fluorobicyclo[1.1.1] pen...)
Affinity DataIC50: 235nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639407((cyclobutylmethyl)({2- [(4- {[1,2,4]triazolo[4,3- ...)
Affinity DataIC50: 236nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639428(({3- fluorobicyclo[1.1.1] pentan-1- yl}methyl)[(2-...)
Affinity DataIC50: 300nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639385(N-[(6- {[(cyclohexylmethyl) amino]methyl} imidazo ...)
Affinity DataIC50: 719nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639393(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 1.07E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639422(3-(1-{[6-({6- azaspiro[3.4]octan- 6- yl}methyl)imi...)
Affinity DataIC50: 1.18E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639390(N-[(6- {[(cyclohexylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 1.19E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639412(US20230391770, Example 32)
Affinity DataIC50: 1.26E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639389(N-[(6- {[(cyclohexylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 1.40E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639396(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 1.60E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639430((cyclobutylmethyl)[(2- {[4-(1-methyl-1H- indazol-7...)
Affinity DataIC50: 2.70E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639386(N-({6- methylimidazo[1,2- a]pyridin-2- yl}methyl)-...)
Affinity DataIC50: 3.25E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639397(N-[(6- {[(cyclobutylmethyl) amino]methyl} imidazo[...)
Affinity DataIC50: 3.82E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639401(1-({6- methylimidazo [1,2-a]pyridin-2- yl}methyl)-...)
Affinity DataIC50: 4.58E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639384(N-({6-methylimidazo[1,2-a]pyridin-2-yl}methyl)-1H-...)
Affinity DataIC50: 5.34E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent

LigandPNGBDBM639400(US20230391770, Example 20)
Affinity DataIC50: 5.40E+3nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent