Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11744
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM643758(Preparation of 4-amino-5-(5-(4-methylpiperazin-1-y...)
Affinity DataIC50: 7.5nMAssay Description:The kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. The 100 ng/μL HPK1 (Life t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM643760(Preparation of 4-amino-5-(5-(4-methylpiperazin-1-y...)
Affinity DataIC50: 8.80nMAssay Description:The kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. The 100 ng/μL HPK1 (Life t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM643759(Preparation of 4-amino-5-(5-(4-methylpiperazin-1-y...)
Affinity DataIC50: 9.20nMAssay Description:The kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. The 100 ng/μL HPK1 (Life t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM643757(US20240002394, Example 2)
Affinity DataIC50: 9.70nMAssay Description:The kinase buffer (Enzymatic buffer 5×) was diluted to 1×, and 10 mM MgCl2, 1 mM DTT, and 0.005% Tween 20 were added. The 100 ng/μL HPK1 (Life t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent