Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 11755 Sort by
TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645010(US20240010639, Example 14 | (S)-6-((1-(2-Fluoro-5-...)
Affinity DataIC50: 350nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645002(US20240010639, Example 6 | (S)-6-((1-(5-Cyclopropy...)
Affinity DataIC50: 450nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645006(US20240010639, Example 10)
Affinity DataIC50: 620nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645005(US20240010639, Example 9 | (S)-6-((l-(2,3-Dihydro-...)
Affinity DataIC50: 680nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645008(US20240010639, Example 12 | (S)-6-((1-(2-Fluoro-5-...)
Affinity DataIC50: 810nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645009(US20240010639, Example 13 | (S)-6-((1-(2-Fluoro-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645012(US20240010639, Example 16 | (S)-6-((1-(2-Fluoro-5-...)
Affinity DataIC50: 1.06E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645011(US20240010639, Example 15 | (S)-6-((1-(3-((6-Methy...)
Affinity DataIC50: 1.13E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645003(US20240010639, Example 7 | (S)-6-((1-(Bicyclo[4.2....)
Affinity DataIC50: 1.33E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645007(US20240010639, Example 11 | (S)-6-((1-(5-Fluoro-2,...)
Affinity DataIC50: 1.39E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645000(US20240010639, Example 4 | (S)-3-Isopropyl-6-((1-(...)
Affinity DataIC50: 1.66E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645001(US20240010639, Example 5 | (S)-3-Isopropyl-6-((1-(...)
Affinity DataIC50: 1.98E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644997(US20240010639, Example 1 | 6-(((S)-1-(2-Fluoro-5-(...)
Affinity DataIC50: 2.41E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644998(US20240010639, Example 2 | 6-(((S)-1-(2-Fluoro-5-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM645004(US20240010639, Example 8 | (S)-6-((1-(2,3-Dihydrob...)
Affinity DataIC50: 3.75E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMyosin-1(Human)
Jiangsu Hengrui Pharmaceuticals Co.

US Patent
LigandPNGBDBM644999(US20240010639, Example 3 | 3-Isopropyl-6-(((1S)-1-...)
Affinity DataIC50: 5.11E+3nMAssay Description:Myocardial actin (1.61 μM) and myosin motor protein S 1 fragment (0.07 μM) were mixed with different concentrations of small-molecule compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent