Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 11763
TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM547567(US11292791, Example 840 | US20240016795, Compound ...)
Affinity DataIC50: 10nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM547567(US11292791, Example 840 | US20240016795, Compound ...)
Affinity DataIC50: 10nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2024
Entry Details
US Patent

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM645365(US20240016795, Compound 1 | Synthesis of (1R,3R)-3...)
Affinity DataIC50: 10nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2024
Entry Details
US Patent

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM645375(US20240016795, Compound 2 | Synthesis of (1R,3R)-3...)
Affinity DataIC50: 10nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2024
Entry Details
US Patent

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM645373(US20240016795, Compound 1')
Affinity DataIC50: 20nMAssay Description:The potency and selectivity of CBP/P300 inhibitor compounds including Compound 1 were determined in biochemical time resolved fluorescence assays usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2024
Entry Details
US Patent