Compile Data Set for Download or QSAR
Report error Found 294 Enz. Inhib. hit(s) with all data for entry = 11778
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646601BDBM646601(6-chloro-7- (difluoromethylthio)-N-[5-(2- fluoroet...)
Affinity DataIC50: 7nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646556BDBM646556(6-chloro-N-[5-(3- fluoropropyl)-4,6-dimethoxy- pyr...)
Affinity DataIC50: 7nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646555BDBM646555(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)
Affinity DataIC50: 8nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646694BDBM646694(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 8nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646738BDBM646738(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)
Affinity DataIC50: 9nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646563BDBM646563(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 9nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646588BDBM646588(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)
Affinity DataIC50: 10nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646598BDBM646598(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646548BDBM646548(6-chloro-N-[5-(2- fluoroethoxy)-4,6-dimethoxy- pyr...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646655BDBM646655(6-bromo-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl)...)
Affinity DataIC50: 11nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646602BDBM646602(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646516BDBM646516(6-chloro-N-[5-(3- fluoropropyl)-4-methoxy- pyrimid...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646557BDBM646557(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)
Affinity DataIC50: 12nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646681BDBM646681(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646554BDBM646554(6-chloro-N-[5-(2-fluoroethyl)- 4,6-dimethoxy-pyrim...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646778BDBM646778(US20240025883, Example 283)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646551BDBM646551(N-(5-allyl-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646606BDBM646606(US20240025883, Example 288 | 6-bromo-N-[5-(2,2- di...)
Affinity DataIC50: 13nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646713BDBM646713(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646747BDBM646747(US20240025883, Example 253 | N-[5-(2-cyanoethyl)-4...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646731BDBM646731(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646636BDBM646636(7-bromo-6-chloro-N-[5-(2- fluoroethoxy)-4-methoxy-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646597BDBM646597(N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646600BDBM646600(6-chloro-N-[5-(2-cyanoethyl)- 4-methoxy-pyrimidin-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646760BDBM646760(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646564BDBM646564(6-chloro-N-(5-cyclopropyl- 4,6-dimethoxy-pyrimidin...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646702BDBM646702(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646667BDBM646667(US20240025883, Example 172)
Affinity DataIC50: 15nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646729BDBM646729(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646616BDBM646616(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646691BDBM646691(6-bromo-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrim...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646739BDBM646739(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646607BDBM646607(6-bromo-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy-...)
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646553BDBM646553(6-chloro-N-(4,6-dimethoxy-5- propyl-pyrimidin-2-yl...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646549BDBM646549(6-chloro-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646550BDBM646550(6-chloro-N-[4,6-dimethoxy-5- (1,1,2- trifluoroetho...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646712BDBM646712(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)
Affinity DataIC50: 17nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646682BDBM646682(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646714BDBM646714(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646587BDBM646587(6-bromo-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy-...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646705BDBM646705(6,7-dichloro-N-[5-(2,2- difluoroethyl)-4-methoxy- ...)
Affinity DataIC50: 18nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646741BDBM646741(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646561BDBM646561(6-chloro-N-[4,6-dimethoxy-5- (2-methoxyethyl)pyrim...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646542BDBM646542(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646512BDBM646512(6-chloro-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl...)
Affinity DataIC50: 19nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646507BDBM646507(N-(5-bromo-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646747BDBM646747(US20240025883, Example 253 | N-[5-(2-cyanoethyl)-4...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646664BDBM646664(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646687BDBM646687(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 646726BDBM646726(6-bromo-N-[4-methoxy-5- (1,1,2- trifluoroethoxy)py...)
Affinity DataIC50: 21nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

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