Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 11832
TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651947BDBM651947(US20240051958, Example 18)
Affinity DataIC50: 0.100nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651946BDBM651946(US20240051958, Example 17)
Affinity DataIC50: 0.120nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651949BDBM651949(US20240051958, Example 20)
Affinity DataIC50: 0.130nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651957BDBM651957(US20240051958, Example 28)
Affinity DataIC50: 0.140nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651951BDBM651951(US20240051958, Example 22)
Affinity DataIC50: 0.150nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651944BDBM651944(US20240051958, Example 15)
Affinity DataIC50: 0.190nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651950BDBM651950(US20240051958, Example 21)
Affinity DataIC50: 0.230nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651952BDBM651952(US20240051958, Example 23)
Affinity DataIC50: 0.270nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651953BDBM651953(US20240051958, Example 24)
Affinity DataIC50: 0.310nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651945BDBM651945(US20240051958, Example 16)
Affinity DataIC50: 0.350nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651939BDBM651939(US20240051958, Example 10)
Affinity DataIC50: 0.360nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651931BDBM651931(US20240051958, Example 2)
Affinity DataIC50: 0.470nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651959BDBM651959(US20240051958, Example 30)
Affinity DataIC50: 0.650nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651940BDBM651940(US20240051958, Example 11)
Affinity DataIC50: 0.660nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651958BDBM651958(US20240051958, Example 29)
Affinity DataIC50: 0.700nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651935BDBM651935(US20240051958, Example 6)
Affinity DataIC50: 1.23nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651941BDBM651941(US20240051958, Example 12)
Affinity DataIC50: 1.35nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651930BDBM651930(US20240051958, Example 1)
Affinity DataIC50: 1.99nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651938BDBM651938(US20240051958, Example 9)
Affinity DataIC50: 2.04nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651932BDBM651932(US20240051958, Example 3)
Affinity DataIC50: 2.35nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651948BDBM651948(US20240051958, Example 19)
Affinity DataIC50: 2.36nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651955BDBM651955(US20240051958, Example 26)
Affinity DataIC50: 3.34nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651942BDBM651942(US20240051958, Example 13)
Affinity DataIC50: 4.11nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651933BDBM651933(US20240051958, Example 4)
Affinity DataIC50: 4.43nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651954BDBM651954(US20240051958, Example 25)
Affinity DataIC50: 5.29nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651937BDBM651937(US20240051958, Example 8)
Affinity DataIC50: 7.74nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651956BDBM651956(US20240051958, Example 27)
Affinity DataIC50: 13.6nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651936BDBM651936(US20240051958, Example 7)
Affinity DataIC50: 16nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651934BDBM651934(US20240051958, Example 5)
Affinity DataIC50: 103nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 651943BDBM651943(US20240051958, Example 14 | US20250223301, Compoun...)
Affinity DataIC50: 143nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent