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Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 11853
TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653556(3-(7′-oxo-7′,9′-dihydro-2′...)
Affinity DataIC50:  259nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653555((S)-3-(7′-oxo-7′,9′-dihydro-2...)
Affinity DataIC50:  330nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653552(3-(7'-oxo-3',4',7',9'-tetrahydro- 8'H-spiro[piperi...)
Affinity DataIC50:  620nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653551(3-(7'-oxo-7',9'-dihydro-8'H- spiro[piperidine-4,2'...)
Affinity DataIC50:  1.10E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653553(3-(7'-oxo-7',9'-dihydro-8'H- spiro[azetidine-3,2'-...)
Affinity DataIC50:  1.30E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653557((S)-3-(5′-fluoro-6′-oxo-6′,8R...)
Affinity DataIC50:  1.73E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653558((S)-3-(6′-oxo-6′,8′-dihydro-3...)
Affinity DataIC50:  4.33E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653559(7′-(2,6-dioxopiperidin-3-yl)-7′-hydro-...)
Affinity DataIC50:  4.63E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653554(3-(7'-oxo-3',4',7',9'-tetrahydro- 8'H-spiro[azetid...)
Affinity DataIC50:  5.20E+3nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent