Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 11892
TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602445BDBM50602445(CHEMBL5207542 | US20240083885, Compound Jun9-4-4)
Affinity DataIC50: 0.280nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602446BDBM50602446(CHEMBL5178131 | US20240083885, Compound Jun8-66-1)
Affinity DataIC50: 0.510nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602449BDBM50602449(CHEMBL5201613 | US20240083885, Compound Jun9-5-2)
Affinity DataIC50: 0.670nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602450BDBM50602450(CHEMBL5172431 | US20240083885, Compound Jun8-76-4)
Affinity DataIC50: 0.810nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602451BDBM50602451(CHEMBL5189062 | US20240083885, Compound Jun8-76-5)
Affinity DataIC50: 0.940nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602452BDBM50602452(CHEMBL5208393 | US20240083885, Compound Jun8-90-3)
Affinity DataIC50: 0.960nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602453BDBM50602453(CHEMBL5179577 | US20240083885, Compound Jun9-12-2)
Affinity DataIC50: 1.06nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602454BDBM50602454(CHEMBL5204664 | US20240083885, Compound Jun9-5-3)
Affinity DataIC50: 1.48nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602455BDBM50602455(CHEMBL5175491 | US20240083885, Compound Jun9-6-4)
Affinity DataIC50: 1.81nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602456BDBM50602456(CHEMBL5198265 | US20240083885, Compound Jun8-75-2)
Affinity DataIC50: 1.97nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602459BDBM50602459(CHEMBL5196047 | US20240083885, Compound Jun8-92-1)
Affinity DataIC50: 2.47nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602460BDBM50602460(CHEMBL5193830 | US20240083885, Compound Jun8-88-2)
Affinity DataIC50: 2.51nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602461BDBM50602461(CHEMBL5182370 | US20240083885, Compound Jun8-91-5)
Affinity DataIC50: 2.54nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602462BDBM50602462(CHEMBL5176045 | US20240083885, Compound Jun9-3-3)
Affinity DataIC50: 2.68nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602463BDBM50602463(CHEMBL5193986 | US20240083885, Compound Jun8-58-2)
Affinity DataIC50: 3.86nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602464BDBM50602464(CHEMBL5170916 | US20240083885, Compound Jun9-3-2)
Affinity DataIC50: 4.10nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 429456BDBM429456(med.21724, Compound 128 | acs.jmedchem.1c00409_ST....)
Affinity DataIC50: 4.93nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602465BDBM50602465(CHEMBL5190815 | US20240083885, Compound Jun8-92-2)
Affinity DataIC50: 4.99nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602466BDBM50602466(CHEMBL5188059 | US20240083885, Compound Jun8-88-1)
Affinity DataIC50: 5.37nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602467BDBM50602467(CHEMBL5171513 | US20240083885, Compound Jun8-97-1)
Affinity DataIC50: 5.46nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602468BDBM50602468(CHEMBL5170231 | US20240083885, Compound Jun8-56-1)
Affinity DataIC50: 5.70nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602469BDBM50602469(CHEMBL5179593 | US20240083885, Compound Jun9-4-2)
Affinity DataIC50: 5.82nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 657968BDBM657968(US20240083885, Compound Jun9-3-5)
Affinity DataIC50: 7.27nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602471BDBM50602471(CHEMBL5171462 | US20240083885, Compound Jun9-88-4)
Affinity DataIC50: 7.49nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602472BDBM50602472(CHEMBL5188623 | US20240083885, Compound Jun9-88-3)
Affinity DataIC50: 7.81nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602473BDBM50602473(CHEMBL5192910 | US20240083885, Compound Jun8-74-1)
Affinity DataIC50: 8.13nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 429328BDBM429328(jm5b01461, Compound 146 | ALP-POS-c59291d4-6 | CVD...)
Affinity DataIC50: 11nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602464BDBM50602464(CHEMBL5170916 | US20240083885, Compound Jun9-3-2)
Affinity DataIC50: 12.1nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496109BDBM496109(ALP-POS-02c6a514-57 | CVD-0013887 | US20240083885,...)
Affinity DataIC50: 13.2nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602447BDBM50602447(CHEMBL5169554 | US20240083885, Compound Jun8-91-4)
Affinity DataIC50: 14.6nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602477BDBM50602477(CHEMBL5178977 | US20240083885, Compound Jun8-50-3)
Affinity DataIC50: 20nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602476BDBM50602476(CHEMBL5189716 | US20240083885, Compound Jun8-50-4)
Affinity DataIC50: 20nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602478BDBM50602478(CHEMBL2311738 | US20240083885, Compound Jun8-59-2)
Affinity DataIC50: 20nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602479BDBM50602479(CHEMBL3605708 | US20240083885, Compound Jun8-58-3)
Affinity DataIC50: 20nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602480BDBM50602480(CHEMBL5170981 | US20240083885, Compound Jun9-5-4)
Affinity DataIC50: 21.9nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602481BDBM50602481(CHEMBL5195155 | US20240083885, Compound Jun8-92-4)
Affinity DataIC50: 35.1nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 657959BDBM657959(US20240083885, Compound Jun8-91-6)
Affinity DataIC50: 37.3nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Arizona Board Of Regents On Behalf Of The University Of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 50602448BDBM50602448(CHEMBL5186431 | US20240083885, Compound Jun8-76-3)
Affinity DataIC50: 310nMAssay Description:The main protease (Mpro) enzymatic assays were carried out exact as previously described in pH 6.5 reaction buffer containing 20 mM HEPES pH 6.5, 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent