Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 11915
TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660583(US20240092803, Example 12)
Affinity DataIC50: 9.80nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660582(US20240092803, Example 11)
Affinity DataIC50: 12nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660581(US20240092803, Example 10)
Affinity DataIC50: 22nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660584(US20240092803, Example 13)
Affinity DataIC50: 27nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660586(US20240092803, Example 15)
Affinity DataIC50: 41nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660578(US20240092803, Example 7)
Affinity DataIC50: 59nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660580(US20240092803, Example 9)
Affinity DataIC50: 63nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660576(US20240092803, Example 5)
Affinity DataIC50: 118nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660585(US20240092803, Example 14)
Affinity DataIC50: 126nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660574(US20240092803, Example 3)
Affinity DataIC50: 635nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660577(US20240092803, Example 6)
Affinity DataIC50: 713nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660579(US20240092803, Example 8)
Affinity DataIC50: 749nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660583(US20240092803, Example 12)
Affinity DataIC50: 2.39E+3nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660575(US20240092803, Example 4)
Affinity DataIC50: 2.59E+3nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660582(US20240092803, Example 11)
Affinity DataIC50: 3.62E+3nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660573(US20240092803, Example 2)
Affinity DataIC50: 4.50E+3nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660581(US20240092803, Example 10)
Affinity DataIC50: 6.21E+3nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660580(US20240092803, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660586(US20240092803, Example 15)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660579(US20240092803, Example 8)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660584(US20240092803, Example 13)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660585(US20240092803, Example 14)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660578(US20240092803, Example 7)
Affinity DataIC50: 1.72E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660496(US20240092803, Example 1)
Affinity DataIC50: 2.27E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660573(US20240092803, Example 2)
Affinity DataIC50: 3.42E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660574(US20240092803, Example 3)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660575(US20240092803, Example 4)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660496(US20240092803, Example 1)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660576(US20240092803, Example 5)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Beigene Switzerland

US Patent
LigandPNGBDBM660577(US20240092803, Example 6)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay was used to identify compounds which competitively interact with the binding of KRAS protein to SOS1 in the presence of GDP. GST-tagged WT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent