Compile Data Set for Download or QSAR
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Report error Found 427 Enz. Inhib. hit(s) with all data for entry = 11918
TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660837(N-(6-chloropyridin-3-yl)-6- (oxetan-3- ylmethoxy)i...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660838((R)-3-((1-((6-chloropyridin-3- yl)amino)isoquinoli...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660839((S)-3-((1-((6-chloropyridin-3- yl)amino)isoquinoli...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660840(6-(2-amino-3,3,3- trifluoropropoxy)-N-(6- chloropy...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660841((R)-N-(6-chloropyridin-3-yl)-6- ((4,4-difluoropyrr...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660842(3-(((1-((2-methylpyrimidin-5- yl)amino)isoquinolin...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660843(N-(6-chloropyridin-3-yl)-6- (cyclopropylmethoxy)-5...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660844(N1-(6-chloropyridin-3-yl)-N6- (cyclopropylmethyl)i...)
Affinity DataEC50:  2.00E+4nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660845(N-(6-chloropyridin-3-yl)-6-((1- (trifluoromethyl)c...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660846(N1-(6-chloropyridin-3-yl)-N6- (cyclopropylmethyl)-...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660847(6-(cyclopropylmethoxy)-5- fluoro-N-(2-methylpyrimi...)
Affinity DataEC50:  2.00E+4nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660848(1-(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660849(3,3-difluoro-1-(((1-((2- methylpyrimidin-5- yl)ami...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660850(N-(6-chloropyridin-3-yl)-6-(2- (2- methoxyethoxy)e...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660851((S)-N-(6-chloropyridin-3-yl)-6- (1-(pyridin-4- yl)...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660852((1-(((1-((6-chloropyridin-3- yl)amino)isoquinolin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660853(N-(6-chloropyridin-3-yl)-6-((4- fluorotetrahydro-2...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660854(3-((1-((6-chloropyridin-3- yl)amino)isoquinolin-6-...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660855(6-(isoxazol-4-ylmethoxy)-N- (2-methylpyrimidin-5- ...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660856(N-(2-chloropyrimidin-5-yl)-6- (isoxazol-4- ylmetho...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660857(1-((2-chloropyrimidin-5- yl)amino)isoquinolin-6-ol...)
Affinity DataEC50:  2.00E+4nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660858(N1-(6-chloropyridin-3-yl)-N6- ((1-methyl-1H-pyrazo...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660859(N1-(6-chloropyridin-3-yl)-N6- ((3-methyloxetan-3- ...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660860((E)-3-(1-((6-chloropyridin-3- yl)amino)isoquinolin...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660861(N-(6-chloropyridin-3-yl)-7- fluoro-6-((1- fluorocy...)
Affinity DataEC50:  2.00E+4nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660862(6-(((1H-pyrazol-4- yl)amino)methyl)-N-(6- chloropy...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660863(N-(6-chloropyridin-3-yl)-6-(((1- methyl-1H-pyrazol...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660864(N-(6-chloropyridin-3-yl)-6- ((methyl(1H-pyrazol-4-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660865(N6-(6-chloropyridin-3-yl)-N3- ((1-methyl-1H-pyrazo...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660866(N-(6-chloropyridin-3-yl)-3-((1- methyl-1H-pyrazol-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660865(N6-(6-chloropyridin-3-yl)-N3- ((1-methyl-1H-pyrazo...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660868(1-(((8-((2-chloropyrimidin-5- yl)amino)-1,7-naphth...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660869(N-(6-chloropyridin-3-yl)-3- (cyclopropylmethoxy)-1...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660870(3-(cyclopropylmethoxy)-N-(6- methylpyridin-3-yl)-1...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660871(3-(cyclopropylmethoxy)-N-(2- methylpyrimidin-5-yl)...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660872(3-((1-methyl-1H-pyrazol-4- yl)methoxy)-N-(2- methy...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660873(N-(6-chloropyridin-3-yl)-3-((3- methyloxetan-3-yl)...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660874(6-(3-(1H-pyrazol-4- yl)propoxy)-N-(6- chloropyridi...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660875((R)-3-((1-((6-chloropyridin-3- yl)amino)isoquinoli...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660876((S)-3-((1-((6-chloropyridin-3- yl)amino)isoquinoli...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660877(N-(6-chloropyridin-3-yl)-6- ((tetrahydrofuran-3- y...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660878(Synthesis of trans-4-((1-((6-chloropyridin-3-yl)am...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660879(Synthesis of trans-4-((1-((6-chloropyridin-3-yl)am...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660880(N-(6-chloropyridin-3-yl)-6- (pyridin-3-yloxy)isoqu...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660881(6-((1H-pyrazol-4-yl)oxy)-N-(6- chloropyridin-3-yl)...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660882(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6- y...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660883(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6- y...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660884(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6- y...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660885(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6- y...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660886(((1-((6-chloropyridin-3- yl)amino)isoquinolin-6- y...)
Affinity DataEC50:  5.50E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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