Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 11939
TargetCREB-binding protein(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662966BDBM662966(US20240109879, Compound 2B)
Affinity DataIC50: 0.670nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetCREB-binding protein(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662967BDBM662967(US20240109879, Compound 3B)
Affinity DataIC50: 0.670nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662970BDBM662970(US20240109879, Compound 6B)
Affinity DataIC50: 2.09nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662967BDBM662967(US20240109879, Compound 3B)
Affinity DataIC50: 2.88nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetCREB-binding protein(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662974BDBM662974(US20240109879, Compound 10B)
Affinity DataIC50: 3.13nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662966BDBM662966(US20240109879, Compound 2B)
Affinity DataIC50: 3.54nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662974BDBM662974(US20240109879, Compound 10B)
Affinity DataIC50: 4.08nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662971BDBM662971(US20240109879, Compound 7B)
Affinity DataIC50: 4.11nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662975BDBM662975(US20240109879, Compound 11B)
Affinity DataIC50: 5.48nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662972BDBM662972(US20240109879, Compound 8C)
Affinity DataIC50: 10.3nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662973BDBM662973(US20240109879, Compound 9B)
Affinity DataIC50: 11nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662969BDBM662969(US20240109879, Compound 4A)
Affinity DataIC50: 11.3nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 662968BDBM662968(US20240109879, Compound 3C)
Affinity DataIC50: 14.1nMAssay Description:Reagent:Reaction buffer: 25 mM HEPES, pH 7.5, 25 mM NaCl, 0.025% CHAPS, 0.025% BSA, 0.5% DMSO.Ligand:Histone H4 (1-21) K5/8/12/16Ac-GG-Biotin.Standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent