Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 11955
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 290431BDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 54.5nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664709BDBM664709(US20240116873, Compound D)
Affinity DataIC50: 80.4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50158460BDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 585nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50158460BDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.09E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664709BDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.16E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664708BDBM664708(US20240116873, Compound C)
Affinity DataIC50: 1.18E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664707BDBM664707(US20240116873, Compound B)
Affinity DataIC50: 2.79E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664704BDBM664704(US20240116873, Compound A)
Affinity DataIC50: 3.15E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664711BDBM664711(US20240116873, Compound E)
Affinity DataIC50: 3.42E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 6(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 6.51E+3nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 6(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664709BDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.27E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 11(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 2.74E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 8(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 4.04E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 11(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664709BDBM664709(US20240116873, Compound D)
Affinity DataIC50: 8.38E+4nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetSolute carrier family 22 member 8(Human)
JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 664709BDBM664709(US20240116873, Compound D)
Affinity DataIC50: 1.00E+5nMAssay Description:Experimental results: The compounds had no obvious inhibitory effect on the drug transporter OAT3, and when the compounds were used clinically in com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent