Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 11989
TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668460(N-((1s,3s)-3- methoxycyclobutyl)-2-(1-(2- methoxye...)
Affinity DataIC50: 3.00E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668458(6-(1-Isopropyl-1H-pyrazol-3-yl)- N-((1S,3R)-3- met...)
Affinity DataIC50: 3.00E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetGTPase KRas [Q61H]/Son of sevenless homolog 1(Human)
Shy Therapeutics

US Patent
LigandPNGBDBM668459(rac-6-(1-Isopropyl-1H-pyrazol- 3-yl)-N-((1R,3S)-3-...)
Affinity DataIC50: 7.50E+3nMAssay Description:The small GTPases proteins cdc42 and Rheb were expressed as His-tagged proteins. For the assay, the cdc42 and Rheb purified small GTPases proteins we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent