Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 11990
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668469BDBM668469(US20240124487, Compound 9)
Affinity DataKi:  0.00900nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668463BDBM668463(US20240124487, Compound 3 | US20240124487, Compoun...)
Affinity DataKi:  0.00900nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668466BDBM668466(US20240124487, Compound 6)
Affinity DataKi:  0.00900nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668477BDBM668477(US20240124487, Compound 17 | US20240124487, Compou...)
Affinity DataKi:  0.0100nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668470BDBM668470(US20240124487, Compound 10 | US20240124487, Compou...)
Affinity DataKi:  0.0100nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668465BDBM668465(US20240124487, Compound 5)
Affinity DataKi:  0.0110nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668467BDBM668467(US20240124487, Compound 7)
Affinity DataKi:  0.0110nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668468BDBM668468(US20240124487, Compound 8)
Affinity DataKi:  0.0130nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668486BDBM668486(US20240124487, Compound 27 | US20240124487, Compou...)
Affinity DataKi:  0.0130nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668472BDBM668472(US20240124487, Compound 12 | US20240124487, Compou...)
Affinity DataKi:  0.0150nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668474BDBM668474(US20240124487, Compound 14)
Affinity DataKi:  0.0180nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668479BDBM668479(US20240124487, Compound 19 | US20240124487, Compou...)
Affinity DataKi:  0.0230nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668461BDBM668461(US20240124487, Compound 1 | US20240124487, Compoun...)
Affinity DataKi:  0.0240nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668490BDBM668490(US20240124487, Compound 31 | US20240124487, Compou...)
Affinity DataKi:  0.0280nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668470BDBM668470(US20240124487, Compound 10 | US20240124487, Compou...)
Affinity DataKi:  0.0280nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668486BDBM668486(US20240124487, Compound 27 | US20240124487, Compou...)
Affinity DataKi:  0.0340nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668463BDBM668463(US20240124487, Compound 3 | US20240124487, Compoun...)
Affinity DataKi:  0.0390nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668477BDBM668477(US20240124487, Compound 17 | US20240124487, Compou...)
Affinity DataKi:  0.0420nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668475BDBM668475(US20240124487, Compound 15 | US20240124487, Compou...)
Affinity DataKi:  0.0480nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668479BDBM668479(US20240124487, Compound 19 | US20240124487, Compou...)
Affinity DataKi:  0.0570nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668481BDBM668481(US20240124487, Compound 21)
Affinity DataKi:  0.0570nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668473BDBM668473(US20240124487, Compound 13)
Affinity DataKi:  0.0580nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668461BDBM668461(US20240124487, Compound 1 | US20240124487, Compoun...)
Affinity DataKi:  0.0590nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668482BDBM668482(US20240124487, Compound 22 | US20240124487, Compou...)
Affinity DataKi:  0.0730nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668475BDBM668475(US20240124487, Compound 15 | US20240124487, Compou...)
Affinity DataKi:  0.104nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668486BDBM668486(US20240124487, Compound 27 | US20240124487, Compou...)
Affinity DataKi:  0.302nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668482BDBM668482(US20240124487, Compound 22 | US20240124487, Compou...)
Affinity DataKi:  0.357nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668490BDBM668490(US20240124487, Compound 31 | US20240124487, Compou...)
Affinity DataKi:  0.408nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668485BDBM668485(US20240124487, Compound 26)
Affinity DataKi:  3.61nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668472BDBM668472(US20240124487, Compound 12 | US20240124487, Compou...)
Affinity DataKi:  8.42nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 668486BDBM668486(US20240124487, Compound 27 | US20240124487, Compou...)
Affinity DataKi:  44.2nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent