Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12004
TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669593BDBM669593(US20240132477, Example 31)
Affinity DataIC50: 3nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669592BDBM669592(US20240132477, Example 30)
Affinity DataIC50: 3nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669525BDBM669525(US20240132477, Example 1)
Affinity DataIC50: 3nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669583BDBM669583(US20240132477, Example 21)
Affinity DataIC50: 4nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669582BDBM669582(US20240132477, Example 20)
Affinity DataIC50: 4nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669564BDBM669564(US20240132477, Example 2)
Affinity DataIC50: 4nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669596BDBM669596(US20240132477, Example 34)
Affinity DataIC50: 4nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669598BDBM669598(US20240132477, Example 36)
Affinity DataIC50: 5nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669584BDBM669584(US20240132477, Example 22)
Affinity DataIC50: 5nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669595BDBM669595(US20240132477, Example 33)
Affinity DataIC50: 5nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669597BDBM669597(US20240132477, Example 35)
Affinity DataIC50: 5nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669591BDBM669591(US20240132477, Example 29)
Affinity DataIC50: 6nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669588BDBM669588(US20240132477, Example 26)
Affinity DataIC50: 6nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669575BDBM669575(US20240132477, Example 13)
Affinity DataIC50: 7nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669574BDBM669574(US20240132477, Example 12)
Affinity DataIC50: 7nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669590BDBM669590(US20240132477, Example 28)
Affinity DataIC50: 7nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669600BDBM669600(US20240132477, Example 38)
Affinity DataIC50: 7nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669594BDBM669594(US20240132477, Example 32)
Affinity DataIC50: 8nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669581BDBM669581(US20240132477, Example 19)
Affinity DataIC50: 8nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669585BDBM669585(US20240132477, Example 23)
Affinity DataIC50: 10nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669579BDBM669579(US20240132477, Example 17)
Affinity DataIC50: 10nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669602BDBM669602(US20240132477, Example 40)
Affinity DataIC50: 13nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669569BDBM669569(US20240132477, Example 7)
Affinity DataIC50: 13nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669567BDBM669567(US20240132477, Example 5)
Affinity DataIC50: 16nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669571BDBM669571(US20240132477, Example 9)
Affinity DataIC50: 20nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669570BDBM669570(US20240132477, Example 8)
Affinity DataIC50: 20nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669578BDBM669578(US20240132477, Example 16)
Affinity DataIC50: 23nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669573BDBM669573(US20240132477, Example 11)
Affinity DataIC50: 31nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669586BDBM669586(US20240132477, Example 24)
Affinity DataIC50: 37nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669568BDBM669568(US20240132477, Example 6)
Affinity DataIC50: 37nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669577BDBM669577(US20240132477, Example 15)
Affinity DataIC50: 42nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669576BDBM669576(US20240132477, Example 14)
Affinity DataIC50: 47nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669572BDBM669572(US20240132477, Example 10)
Affinity DataIC50: 49nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669580BDBM669580(US20240132477, Example 18)
Affinity DataIC50: 54nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669599BDBM669599(US20240132477, Example 37)
Affinity DataIC50: 61nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669566BDBM669566(US20240132477, Example 4)
Affinity DataIC50: 71nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669587BDBM669587(US20240132477, Example 25)
Affinity DataIC50: 72nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669601BDBM669601(US20240132477, Example 39)
Affinity DataIC50: 74nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669589BDBM669589(US20240132477, Example 27)
Affinity DataIC50: 77nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669565BDBM669565(US20240132477, Example 3)
Affinity DataIC50: 821nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent