Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 12011
LigandChemical structure of BindingDB Monomer ID 669921BDBM669921(US20240132519, Compound A1)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669915BDBM669915(US20240132519, Compound 48 | Production of 3-(5-ac...)
Affinity DataIC50: 0.150nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669915BDBM669915(US20240132519, Compound 48 | Production of 3-(5-ac...)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669923BDBM669923(US20240132519, Compound B1)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669894BDBM669894(US20240132519, Compound 3 | Production of 3-(4-ace...)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669917BDBM669917(US20240132519, Compound 50 | Production of 3-(5-ac...)
Affinity DataIC50: 0.190nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669907BDBM669907(US20240132519, Compound 16 | Production of 3-(5-ac...)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669902BDBM669902(US20240132519, Compound 11 | Production of 3-(5-ac...)
Affinity DataIC50: 0.230nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669896BDBM669896(US20240132519, Compound 5 | Production of 3-(5-ace...)
Affinity DataIC50: 0.230nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669892BDBM669892(US20240132519, Compound 1 | Production of 3-(5-ace...)
Affinity DataIC50: 0.240nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669893BDBM669893(US20240132519, Compound 2 | Production of 3-(5-ace...)
Affinity DataIC50: 0.25nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669919BDBM669919(US20240132519, Compound 52 | Production of 3-(5-ac...)
Affinity DataIC50: 0.270nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669897BDBM669897(US20240132519, Compound 6 | Production of 3-(5-ace...)
Affinity DataIC50: 0.270nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669903BDBM669903(US20240132519, Compound 12 | Production of 3-(5-ac...)
Affinity DataIC50: 0.280nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669900BDBM669900(US20240132519, Compound 9 | Production of 3-(5-ace...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669901BDBM669901(US20240132519, Compound 10 | Production of 3-(4-ac...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669916BDBM669916(US20240132519, Compound 49 | Production of 3-(5-ac...)
Affinity DataIC50: 0.310nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669899BDBM669899(US20240132519, Compound 8 | Production of 3-(5-ace...)
Affinity DataIC50: 0.360nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669898BDBM669898(US20240132519, Compound 7 | Production of 3-(5-ace...)
Affinity DataIC50: 0.360nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669915BDBM669915(US20240132519, Compound 48 | Production of 3-(5-ac...)
Affinity DataIC50: 0.390nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669914BDBM669914(US20240132519, Compound 23 | Production of 3-[5-(c...)
Affinity DataIC50: 0.390nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669918BDBM669918(US20240132519, Compound 51 | Production of 3-(5-ac...)
Affinity DataIC50: 0.410nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669895BDBM669895(US20240132519, Compound 4 | Production of 3-(5-ace...)
Affinity DataIC50: 0.410nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669904BDBM669904(US20240132519, Compound 13 | Production of 3-(5-ac...)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669922BDBM669922(US20240132519, Compound A2)
Affinity DataIC50: 0.710nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669926BDBM669926(US20240132519, Compound C2)
Affinity DataIC50: 0.890nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669924BDBM669924(US20240132519, Compound B2)
Affinity DataIC50: 1.01nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669905BDBM669905(US20240132519, Compound 14 | Production of 3-(5-ac...)
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669906BDBM669906(US20240132519, Compound 15 | Production of 3-(5-ac...)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669920BDBM669920(US20240132519, Compound 53 | Production of 3-(5-ac...)
Affinity DataIC50: 2.30nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669910BDBM669910(US20240132519, Compound 19 | Production of 3-(5-ca...)
Affinity DataIC50: 3.10nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669912BDBM669912(US20240132519, Compound 21 | Production of 3-(4-ac...)
Affinity DataIC50: 4.60nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669928BDBM669928(US20240132519, Compound D2)
Affinity DataIC50: 5.17nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669913BDBM669913(US20240132519, Compound 22 | Production of 3-(5-ac...)
Affinity DataIC50: 6.10nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669911BDBM669911(US20240132519, Compound 20 | Production of 3-(5-ac...)
Affinity DataIC50: 24nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669908BDBM669908(US20240132519, Compound 17 | Production of 3-(3-{[...)
Affinity DataIC50: 28nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 669909BDBM669909(US20240132519, Compound 18 | Production of 3-(3-{[...)
Affinity DataIC50: 35nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent