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Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12017
TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670420BDBM670420((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670419BDBM670419((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670422BDBM670422((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670424BDBM670424((R)-2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670423BDBM670423((R)-1-(2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazo...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670425BDBM670425((R)-2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.100nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.200nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670426BDBM670426((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 0.200nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670421BDBM670421((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 5.60nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development

US Patent
LigandChemical structure of BindingDB Monomer ID 670418BDBM670418((R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[...)
Affinity DataIC50: 12.2nMAssay Description:BTK kinase domain was expressed and purified as previously reported65. Binding experiments were performed in Tris 20 mM pH=8, 50 mM NaCl, and 1 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent