Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 12019
LigandChemical structure of BindingDB Monomer ID 670766BDBM670766(4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluo...)
Affinity DataIC50: 9nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670723BDBM670723(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 10nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670749BDBM670749(2-cyano-N-[(3R)-1-[3-ethyl-7-(ethylamino)-5-fluoro...)
Affinity DataIC50: 15nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670711BDBM670711(2-chloro-4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-...)
Affinity DataIC50: 15nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670759BDBM670759(5-[[(3S,4S)-1-[3-ethyl-7-(ethylamino)-5-fluoro-2-o...)
Affinity DataIC50: 16nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670724BDBM670724(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 17nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670769BDBM670769((3R,4R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-2...)
Affinity DataIC50: 17nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670764BDBM670764(1-cyano-N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-me...)
Affinity DataIC50: 18nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670770BDBM670770(US20240140933, Example 60B | (3R,4R)-1-[(3R)-7-(et...)
Affinity DataIC50: 21nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670773BDBM670773(US20240140933, Example 63A | (3S,4S)-1-[(3R)-7-(et...)
Affinity DataIC50: 22nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670755BDBM670755(5-[[(3R,5R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 26nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670756BDBM670756(5-[[(3R,5S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 28nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670727BDBM670727(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 29nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670753BDBM670753(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 32nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670763BDBM670763(N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-o...)
Affinity DataIC50: 32nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670760BDBM670760(5-[[(3S,4S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 33nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670767BDBM670767(4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluo...)
Affinity DataIC50: 34nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670750BDBM670750(2-(2-chloroacetyl)-N-[(3R)-1-[7-(ethylamino)-5-flu...)
Affinity DataIC50: 34nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670719BDBM670719(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 35nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670712BDBM670712(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 35nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670734BDBM670734(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 36nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670729BDBM670729(7-(ethylamino)-5-fluoro-3-[(3R)-3-[4-(2-hydroxyace...)
Affinity DataIC50: 36nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670761BDBM670761(5-[[(3S,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 40nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670752BDBM670752(3-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 41nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670754BDBM670754(7-(ethylamino)-5-fluoro-3-[(3R)-3-[(3-fluorosulfon...)
Affinity DataIC50: 43nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670757BDBM670757(5-[[(3R,5S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 45nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670771BDBM670771(US20240140933, Example 61B | (3R,4R)-1-[(3R)-7-(et...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670721BDBM670721(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670762BDBM670762(N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-o...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670718BDBM670718(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 54nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670732BDBM670732(3-chloro-5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-met...)
Affinity DataIC50: 54nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670768BDBM670768(N-[(3R,4R)-4-[2-(4-cyanophenoxy)phenyl]-1-[7-(ethy...)
Affinity DataIC50: 55nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670748BDBM670748(1-cyano-N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methy...)
Affinity DataIC50: 59nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670758BDBM670758(5-[[(3S,4S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 59nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670738BDBM670738(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 65nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670745BDBM670745(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 65nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670751BDBM670751(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 66nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670744BDBM670744(7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-(4-viny...)
Affinity DataIC50: 68nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670739BDBM670739(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 75nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670772BDBM670772(US20240140933, Example 62B | (3R,4R)-N-benzyl-1-[(...)
Affinity DataIC50: 76nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670765BDBM670765(5-[[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 76nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670713BDBM670713(4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-...)
Affinity DataIC50: 77nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670730BDBM670730(7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-[(6-met...)
Affinity DataIC50: 82nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670747BDBM670747(2-cyano-N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methy...)
Affinity DataIC50: 86nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670731BDBM670731(7-(ethylamino)-5-fluoro-3-[(3R)-3-[(6-hydroxy-3-py...)
Affinity DataIC50: 93nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670746BDBM670746(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 101nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670715BDBM670715(4-[[(3S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 108nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670714BDBM670714(4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-...)
Affinity DataIC50: 109nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670726BDBM670726(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 115nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 670733BDBM670733(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 116nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

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