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Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 12032
TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50197885(CHEMBL3940890 | US20240150297, Compound AG10)
Affinity DataIC50:  160nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580635(CHEMBL5091368 | US20240150297, Compound 18f)
Affinity DataIC50:  200nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50:  210nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580630(CHEMBL5080175 | US20240150297, Compound 18a)
Affinity DataIC50:  220nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580649(CHEMBL5093498 | US20240150297, Compound 22)
Affinity DataIC50:  260nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580634(CHEMBL5080942 | US20240150297, Compound 18e)
Affinity DataIC50:  260nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM673767(3-(4-(3,5-Dimethyl-1H-pyrazol-4-yl)piperazin-1-yl)...)
Affinity DataIC50:  300nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50:  410nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580636(CHEMBL5091475 | US20240150297, Compound 18g)
Affinity DataIC50:  550nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580639(CHEMBL5085751 | US20240150297, Compound 18j)
Affinity DataIC50:  600nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580638(CHEMBL5089791 | US20240150297, Compound 18i)
Affinity DataIC50:  620nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580648(CHEMBL5082364 | US20240150297, Compound 21)
Affinity DataIC50:  670nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580631(CHEMBL5078773 | US20240150297, Compound 18b)
Affinity DataIC50:  780nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580637(CHEMBL5081258 | US20240150297, Compound 18h)
Affinity DataIC50:  1.44E+3nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580637(CHEMBL5081258 | US20240150297, Compound 18h)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580635(CHEMBL5091368 | US20240150297, Compound 18f)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580634(CHEMBL5080942 | US20240150297, Compound 18e)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580649(CHEMBL5093498 | US20240150297, Compound 22)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM673767(3-(4-(3,5-Dimethyl-1H-pyrazol-4-yl)piperazin-1-yl)...)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580636(CHEMBL5091475 | US20240150297, Compound 18g)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580630(CHEMBL5080175 | US20240150297, Compound 18a)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580648(CHEMBL5082364 | US20240150297, Compound 21)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580644(CHEMBL5078103 | US20240150297, Compound 20)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580638(CHEMBL5089791 | US20240150297, Compound 18i)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580639(CHEMBL5085751 | US20240150297, Compound 18j)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM50580644(CHEMBL5078103 | US20240150297, Compound 20)
Affinity DataIC50:  5.30E+3nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580631(CHEMBL5078773 | US20240150297, Compound 18b)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50197885(CHEMBL3940890 | US20240150297, Compound AG10)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
In DepthDetails US Patent