Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 12039
LigandChemical structure of BindingDB Monomer ID 674409BDBM674409(US20240150366, Example 10)
Affinity DataIC50: 33nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674404BDBM674404(US20240150366, Example 8)
Affinity DataIC50: 40nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674405BDBM674405(US20240150366, Example 9)
Affinity DataIC50: 44nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674397BDBM674397(US20240150366, Example 1)
Affinity DataIC50: 44nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674417BDBM674417(US20240150366, Example 19)
Affinity DataIC50: 65nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674420BDBM674420(US20240150366, Example 23)
Affinity DataIC50: 68nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674418BDBM674418(US20240150366, Example 20)
Affinity DataIC50: 70nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674411BDBM674411(US20240150366, Example 12)
Affinity DataIC50: 74nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674399BDBM674399(US20240150366, Example 3)
Affinity DataIC50: 75nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674412BDBM674412(US20240150366, Example 13)
Affinity DataIC50: 77nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674414BDBM674414(US20240150366, Example 15)
Affinity DataIC50: 88nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674402BDBM674402(US20240150366, Example 6)
Affinity DataIC50: 91nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674416BDBM674416(US20240150366, Example 18)
Affinity DataIC50: 92nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674398BDBM674398(US20240150366, Example 2)
Affinity DataIC50: 96nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674400BDBM674400(US20240150366, Example 4)
Affinity DataIC50: 100nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674403BDBM674403(US20240150366, Example 7)
Affinity DataIC50: 105nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674401BDBM674401(US20240150366, Example 5)
Affinity DataIC50: 107nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674410BDBM674410(US20240150366, Example 11)
Affinity DataIC50: 110nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674413BDBM674413(US20240150366, Example 14)
Affinity DataIC50: 143nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674419BDBM674419(US20240150366, Example 22)
Affinity DataIC50: 161nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 674415BDBM674415(US20240150366, Example 16)
Affinity DataIC50: 226nMAssay Description:Using human recombinant KRAS G12D, SOS and c-Raf proteins, the inhibitory activity of subject compounds on the complex formation of the proteins was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent