Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 12096
TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677328(US20240174652, Example 3 | US12421218, Example 60)
Affinity DataIC50: 5nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677331(US20240174652, Example 6 | US12421218, Example 134)
Affinity DataIC50: 6nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677329(US20240174652, Example 4 | US20240174652, Example ...)
Affinity DataIC50: 7nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677334(US20240174652, Example 9 | US12421218, Example 137)
Affinity DataIC50: 11nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677327(US20240174652, Example 2 | US12421218, Example 20)
Affinity DataIC50: 14nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677336(US20240174652, Example 11 | US12421218, Example 16...)
Affinity DataIC50: 15nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677325(US20240174652, Example 1 | US20240174652, Example ...)
Affinity DataIC50: 20nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677335(US20240174652, Example 10 | US12421218, Example 16...)
Affinity DataIC50: 20nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677333(US20240174652, Example 8 | US12421218, Example 136)
Affinity DataIC50: 31nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677329(US20240174652, Example 4 | US20240174652, Example ...)
Affinity DataIC50: 62nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677325(US20240174652, Example 1 | US20240174652, Example ...)
Affinity DataIC50: 67nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677332(US20240174652, Example 7 | US12421218, Example 135)
Affinity DataIC50: 70nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677324(US20240174652, Intermediate 250 in WO2019/138017 (...)
Affinity DataIC50: 4.00E+3nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677322(US20240174652, Example 125 in WO2019/138017 | Exam...)
Affinity DataIC50: 5.60E+3nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677323(US20240174652, Intermediate 250 in WO2019/138017 (...)
Affinity DataIC50: 6.30E+3nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677320(US20240174652, Example 8 in WO2019/138017 | Exampl...)
Affinity DataIC50: 9.85E+3nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM677321(US20240174652, Example 12 in WO2019/138017 | Examp...)
Affinity DataIC50: 1.00E+7nMAssay Description:In Vitro Testing of mGluR4 Potency The in vitro activity of the compounds according to the invention may be investigated as follows: The HEK293 cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent