Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12101
TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678368(US20240174692, Compound 005)
Affinity DataIC50: 0.100nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678369(US20240174692, Compound 007)
Affinity DataIC50: 0.400nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678367(US20240174692, Compound 004)
Affinity DataIC50: 0.5nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678370(US20240174692, Compound 008)
Affinity DataIC50: 1.30nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678374(US20240174692, Compound 016B)
Affinity DataIC50: 6.23nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678371(US20240174692, Compound 020)
Affinity DataIC50: 6.60nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678366(US20240174692, Compound 001)
Affinity DataIC50: 9.20nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678373(US20240174692, Compound 014)
Affinity DataIC50: 12nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678375(US20240174692, Compound 034)
Affinity DataIC50: 22.5nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM678372(US20240174692, Compound 027)
Affinity DataIC50: 38.6nMAssay Description:1) KRAS Nucleotide Exchange Buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent