Compile Data Set for Download or QSAR
Report error Found 193 Enz. Inhib. hit(s) with all data for entry = 12102
TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678403BDBM678403(US20240174696, Compound 128)
Affinity DataKi:  0.00600nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678390BDBM678390(US20240174696, Compound 115)
Affinity DataKi:  0.00600nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678404BDBM678404(US20240174696, Compound 129)
Affinity DataKi:  0.00700nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678399BDBM678399(US20240174696, Compound 124 | 4-(2-(oxetan-3-ylmet...)
Affinity DataKi:  0.00700nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678391BDBM678391(US20240174696, Compound 116)
Affinity DataKi:  0.00800nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678385BDBM678385(US20240174696, Compound 110 | 2-methyl-1-(8-(2-(py...)
Affinity DataKi:  0.00800nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678377BDBM678377(US20240174696, Compound 102 | 4-(2-methyl-2,8-diaz...)
Affinity DataKi:  0.0110nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678422BDBM678422(US20240174696, Compound 147 | 4-(2-cyclopentyl-2,8...)
Affinity DataKi:  0.0130nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678555BDBM678555(US20240174696, Compound 281 | 4-(2-(2,2-difluoroet...)
Affinity DataKi:  0.0150nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678500BDBM678500(US20240174696, Compound 226 | 6-benzyl-2-(3-methyl...)
Affinity DataKi:  0.0160nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678528BDBM678528(US20240174696, Compound 254 | 5-(allyloxy)-2-(pyri...)
Affinity DataKi:  0.0180nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678549BDBM678549(US20240174696, Compound 275 | 8-chloro-5-methoxy-4...)
Affinity DataKi:  0.0200nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678548BDBM678548(US20240174696, Compound 274 | 5-(difluoromethoxy)-...)
Affinity DataKi:  0.0200nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678522BDBM678522(US20240174696, Compound 248 | 5-isopropoxy-2-(pyri...)
Affinity DataKi:  0.0200nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678526BDBM678526(US20240174696, Compound 252 | 5-Methoxy-4-(2-methy...)
Affinity DataKi:  0.0220nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678465BDBM678465(US20240174696, Compound 190 | 6-((4-chloro-1H-pyra...)
Affinity DataKi:  0.0260nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678538BDBM678538(US20240174696, Compound 264 | 5-methoxy-2-(3-methy...)
Affinity DataKi:  0.0260nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678466BDBM678466(US20240174696, Compound 191 | 5-cyclopropyl-2-(pyr...)
Affinity DataKi:  0.0280nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678541BDBM678541(US20240174696, Compound 267 | 5-(fluoromethoxy)-2-...)
Affinity DataKi:  0.0280nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678536BDBM678536(US20240174696, Compound 262 | 8-chloro-2-(5-methyl...)
Affinity DataKi:  0.0280nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678507BDBM678507(US20240174696, Compound 233 | 5-Methoxy-2-(pyridin...)
Affinity DataKi:  0.0280nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678394BDBM678394(US20240174696, Compound 119 | 4-(2-cyclohexyl-2,8-...)
Affinity DataKi:  0.0300nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678524BDBM678524(US20240174696, Compound 250 | 1-(8-(5-methoxy-2-(p...)
Affinity DataKi:  0.0330nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678529BDBM678529(US20240174696, Compound 255 | 5-Methoxy-4-(2-(oxet...)
Affinity DataKi:  0.0340nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678543BDBM678543(US20240174696, Compound 269 | 4-(2-Methyl-2,8-diaz...)
Affinity DataKi:  0.0340nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678542BDBM678542(US20240174696, Compound 268 | 2-Methyl-1-(8-(5-(ox...)
Affinity DataKi:  0.0340nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678417BDBM678417(US20240174696, Compound 142 | 2-(3-methyl-1H-pyraz...)
Affinity DataKi:  0.0370nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678459BDBM678459(US20240174696, Compound 184)
Affinity DataKi:  0.0370nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678519BDBM678519(US20240174696, Compound 245 | 2-methyl-4-(2-(pyrid...)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678470BDBM678470(US20240174696, Compound 195 | 4-(2-methyl-2,8-diaz...)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678420BDBM678420(US20240174696, Compound 145)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678556BDBM678556(US20240174696, Compound 282 | 4-[2-[(3-Fluorooxeta...)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678521BDBM678521(US20240174696, Compound 247 | 2-methyl-4-(4-(2-met...)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678554BDBM678554(US20240174696, Compound 280 | 4-(2-(2,2-difluoroet...)
Affinity DataKi:  0.0390nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678468BDBM678468(US20240174696, Compound 193 | 2-(pyridin-4-yl)-4-(...)
Affinity DataKi:  0.0410nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678545BDBM678545(US20240174696, Compound 271 | 2-methyl-1-(8-(2-(py...)
Affinity DataKi:  0.0410nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678473BDBM678473(US20240174696, Compound 198)
Affinity DataKi:  0.0410nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678547BDBM678547(US20240174696, Compound 273 | 5-methoxy-2-(3-methy...)
Affinity DataKi:  0.0430nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678384BDBM678384(US20240174696, Compound 109 | 2-(8-(2-(pyridin-4-y...)
Affinity DataKi:  0.0430nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678504BDBM678504(US20240174696, Compound 230)
Affinity DataKi:  0.0430nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678424BDBM678424(US20240174696, Compound 149 | 3-(8-(2-(3-methyl-1H...)
Affinity DataKi:  0.0450nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678460BDBM678460(US20240174696, Compound 185)
Affinity DataKi:  0.0470nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678539BDBM678539(US20240174696, Compound 265)
Affinity DataKi:  0.0470nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678432BDBM678432(US20240174696, Compound 157 | 6-benzyl-2-(pyridin-...)
Affinity DataKi:  0.0490nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS1 [590-1130](Homo sapiens (Human))
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678376BDBM678376(US20240174696, Compound 101 | 2-(pyridin-4-yl)-4-(...)
Affinity DataKi:  0.0510nMAssay Description:The LATS1 biochemical assay was performed using the HTRF KinEASE-STK S1 Kit (Cisbio, Cat #62ST1PEC), following the protocol from the manufacturer. Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678381BDBM678381(US20240174696, Compound 106 | 4-(2-cyclopentyl-2,8...)
Affinity DataKi:  0.0530nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678427BDBM678427(US20240174696, Compound 152 | 2-(3-methyl-1H-pyraz...)
Affinity DataKi:  0.0530nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678534BDBM678534(US20240174696, Compound 260 | 5-(Oxetan-3-yloxy)-2...)
Affinity DataKi:  0.0550nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678422BDBM678422(US20240174696, Compound 147 | 4-(2-cyclopentyl-2,8...)
Affinity DataKi:  0.0560nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 678471BDBM678471(US20240174696, Compound 196 | (8-(2-(pyridin-4-yl)...)
Affinity DataKi:  0.0570nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

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