Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 12216
TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688323(US20240189287, Compound BNS808 | 4-chloro-N-[2-(2-...)
Affinity DataKi:  0.600nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688314(US20240189287, Compound BNS804 | 2-(4-chlorophenox...)
Affinity DataKi:  1.16nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688335(US20240189287, Compound BNS822 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.40nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688338(US20240189287, Compound BNS825 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.60nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688330(US20240189287, Compound BNS816 | Ethyl-4-((2-(2-ch...)
Affinity DataKi:  8.93nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688322(US20240189287, Compound BNS807 | N-[2-(2-chlorophe...)
Affinity DataKi:  10nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688327(US20240189287, Compound BNS812 | N-[2-(2-chlorophe...)
Affinity DataKi:  16.3nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688329(US20240189287, Compound BNS815 | N-[2-(2-chlorophe...)
Affinity DataKi:  18nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688195(US20240189287, Compound BNS803 | N-[2-(2-chlorophe...)
Affinity DataKi:  22.4nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688324(US20240189287, Compound BNS809 | N-[2-(2-chlorophe...)
Affinity DataKi:  33.8nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688336(US20240189287, Compound BNS823 | 2-[4-(4-chloroben...)
Affinity DataKi:  56.7nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688325(US20240189287, Compound BNS810 | N-[2-(2-chlorophe...)
Affinity DataKi:  64.5nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688326(US20240189287, Compound BNS811 | N-[2-(2-chlorophe...)
Affinity DataKi:  65.6nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688315(US20240189287, Compound BNS805 | N-[2-(2-chlorophe...)
Affinity DataKi:  77.8nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM50388897(CHEMBL2063250 | US20240189287, Com. 10Q (ref))
Affinity DataKi:  111nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688338(US20240189287, Compound BNS825 | N-[2-(2-chlorophe...)
Affinity DataKi:  127nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688321(US20240189287, Compound BNS806 | N-[2-(2-chlorophe...)
Affinity DataKi:  165nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688331(US20240189287, Compound BNS817 | N-[2-(2-chlorophe...)
Affinity DataKi:  290nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688337(US20240189287, Compound BNS824 | N-[2-(2-chlorophe...)
Affinity DataKi:  456nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688178(US20240189287, Compound BNS801 | N-[2-(2-chlorophe...)
Affinity DataKi:  805nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688333(US20240189287, Compound BNS820 | (2R)-N-[2-(2-chlo...)
Affinity DataKi:  877nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688332(US20240189287, Compound BNS819 | N-[2-(2-chlorophe...)
Affinity DataKi:  922nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688326(US20240189287, Compound BNS811 | N-[2-(2-chlorophe...)
Affinity DataKi:  963nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688325(US20240189287, Compound BNS810 | N-[2-(2-chlorophe...)
Affinity DataKi:  988nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688328(US20240189287, Compound BNS813 | 1-[2-(2-chlorophe...)
Affinity DataKi:  1.13E+3nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688327(US20240189287, Compound BNS812 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.30E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM688334(US20240189287, Compound BNS821 | (2S)-N-[2-(2-chlo...)
Affinity DataKi:  1.40E+3nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688330(US20240189287, Compound BNS816 | Ethyl-4-((2-(2-ch...)
Affinity DataKi:  1.53E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688322(US20240189287, Compound BNS807 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.65E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688323(US20240189287, Compound BNS808 | 4-chloro-N-[2-(2-...)
Affinity DataKi:  1.93E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM50020712(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
Affinity DataIC50: 2.58E+3nMAssay Description:Cardiotoxicity potential of BNS808 and BNS822 on the hERG potassium channels was evaluated using the automated patch clamp method (SyncroPatch 384PE)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688323(US20240189287, Compound BNS808 | 4-chloro-N-[2-(2-...)
Affinity DataIC50: 5.39E+3nMAssay Description:Cardiotoxicity potential of BNS808 and BNS822 on the hERG potassium channels was evaluated using the automated patch clamp method (SyncroPatch 384PE)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688314(US20240189287, Compound BNS804 | 2-(4-chlorophenox...)
Affinity DataKi:  5.70E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688329(US20240189287, Compound BNS815 | N-[2-(2-chlorophe...)
Affinity DataKi:  6.31E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688315(US20240189287, Compound BNS805 | N-[2-(2-chlorophe...)
Affinity DataKi:  8.34E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688324(US20240189287, Compound BNS809 | N-[2-(2-chlorophe...)
Affinity DataKi: >9.11E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688321(US20240189287, Compound BNS806 | N-[2-(2-chlorophe...)
Affinity DataKi: >9.11E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688195(US20240189287, Compound BNS803 | N-[2-(2-chlorophe...)
Affinity DataKi: >9.11E+3nMAssay Description:Human kidney membranes were used as the source material for CB2 receptors. The displacement of specifically bound tritiated CP-55,940 from these memb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bionanosim (Bns

US Patent
LigandPNGBDBM688335(US20240189287, Compound BNS822 | N-[2-(2-chlorophe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Cardiotoxicity potential of BNS808 and BNS822 on the hERG potassium channels was evaluated using the automated patch clamp method (SyncroPatch 384PE)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent