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Report error Found 165 Enz. Inhib. hit(s) with all data for entry = 12121
TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681308(N-(4-((R*)-2-(2,3-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50:  13nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681300(N-(4-(2-(4-Amino-3-fluorophenyl)propyl)-6-(((R)-1-...)
Affinity DataIC50:  16nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681168(N-(4-((R*)-2-(3-Chloro-2-fluorophenyl)propyl)-6-((...)
Affinity DataIC50:  17nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681267(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  17nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681249(N-(4-((R*)-2-(2-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50:  18nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681285(N-(4-(2-(3-Aminophenyl)propyl)-6-(((R)-1-hydroxy-4...)
Affinity DataIC50:  21nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681242(N-(4-((R*)-2-(2,6-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50:  22nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681310(N-(4-((R*)-2-(2-Fluorophenyl)propyl)-6-(((R)-1-hyd...)
Affinity DataIC50:  23nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681270(N-(4-(2-(2,3-Dimethyl-2H-indazol-6-yl)propyl)-6-((...)
Affinity DataIC50:  24nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681297(N-(4-(2-(3-Fluoro-4-(hydroxymethyl)phenyl)propyl)-...)
Affinity DataIC50:  26nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681276(N-(4-(2-(4-Aminophenyl)propyl)-6-(((R)-1-hydroxy-4...)
Affinity DataIC50:  29nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681206(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  30nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681215(N-(4-((R*)-2-(6-Aminopyridin-3-yl)propyl)-6-(((R)-...)
Affinity DataIC50:  30nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681252(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  32nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681183(N-(4-((R*)-2-(3-Fluoro-4-methoxyphenyl)propyl)-6-(...)
Affinity DataIC50:  33nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681255(N-(4-((R*)-2-(2-Fluoropyridin-4-yl)propyl)-6-(((R)...)
Affinity DataIC50:  34nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681274(N-(4-(2-(3,5-Difluoro-4-(hydroxymethyl)phenyl)prop...)
Affinity DataIC50:  34nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681311(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  37nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681268(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  38nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681190(N-(4-((R**)-2-(2-Chloropyridin-4-yl)propyl)-6-(((R...)
Affinity DataIC50:  44nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681278(N-(4-(2-(3-Amino-4-methylphenyl)propyl)-6-(((R)-1-...)
Affinity DataIC50:  45nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681240(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  48nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681245(N-(4-((R*)-2-(2-Fluoro-4-methoxyphenyl)propyl)-6-(...)
Affinity DataIC50:  49nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681210(N-(4-((R*)-2-(4-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50:  52nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681198(N-(4-((R*)-2-(4-Chloro-2,3-difluorophenyl)propyl)-...)
Affinity DataIC50:  52nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681171(N-(4-((R*)-2-(5-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50:  55nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681272(N-(4-(2-(Benzo[d][1,3]dioxol-5-yl)propyl)-6-(((R)-...)
Affinity DataIC50:  58nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681211(N-(4-((R*)-2-(2,3-Difluorophenyl)butyl)-6-(((R)-1-...)
Affinity DataIC50:  63nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681204(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  65nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681250(N-(4-((S*)-2-(2-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50:  73nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681225(N-(4-(2-(Benzo[d]oxazol-6-yl)propyl)-6-(((R)-1-hyd...)
Affinity DataIC50:  76nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681263(N-(4-(2-(2-Fluoro-3-methoxyphenyl)propyl)-6-(((R)-...)
Affinity DataIC50:  77nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681281(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  78nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681188(N-(4-((R*)-2-(2,5-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50:  78nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681294(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  79nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681273(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  84nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681289(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  85nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681266(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  88nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681261(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  90nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681170(N-(4-((R*)-2-(2,4-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50:  96nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681258(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  102nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681224(N-(4-(2-(1H-Indol-5-yl)propyl)-6-(((R)-1-hydroxy-4...)
Affinity DataIC50:  102nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681299(N-(4-(2-(3-Fluoro-2-hydroxyphenyl)propyl)-6-(((R)-...)
Affinity DataIC50:  104nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681222(N-(4-(2-(3-Fluorophenyl)propyl)-6-(((R)-1-hydroxy-...)
Affinity DataIC50:  105nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681306(N-(4-(2-(4-Fluoro-2-hydroxyphenyl)propyl)-6-(((R)-...)
Affinity DataIC50:  110nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681221(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  111nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681256(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  112nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681271(N-(4-(2-(5-Chloro-2-hydroxyphenyl)propyl)-6-(((R)-...)
Affinity DataIC50:  113nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681227(N-(4-(2-(4-((Dimethyl(oxo)-λ6-sulfaneylidene)...)
Affinity DataIC50:  114nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681302(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50:  119nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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