Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 12167
TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683800(US20240217988, Example 10 | (6S,8R)-6-(2,6-difluor...)
Affinity DataIC50: 7.80nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683805(US20240217988, Example 30 | (6S,8R)-6-(4-(((S)-1-(...)
Affinity DataIC50: 8.85nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683798(US20240217988, Example 1 | (6S,8R)-6-(2,6-difluoro...)
Affinity DataIC50: 9nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683803(US20240217988, Example 25 | (6S,8R)-6-(4-((1-(3-fl...)
Affinity DataIC50: 11.4nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683808(US20240217988, Example 33 | (6S,8R)-6-(4-((1-(3-fl...)
Affinity DataIC50: 11.8nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683807(US20240217988, Example 32)
Affinity DataIC50: 14.7nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683801(US20240217988, Example 12 | (6S,8R)-6-(2,6-difluor...)
Affinity DataIC50: 15.6nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683809(US20240217988, Example 34 | (6S,8R)-6-(4-((1-(3-fl...)
Affinity DataIC50: 19.4nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683799(US20240217988, Example 9 | (6S,8R)-7-(2,2-difluoro...)
Affinity DataIC50: 21.6nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683802(US20240217988, Example 14 | (6S,8R)-7-(2,2-difluor...)
Affinity DataIC50: 40.3nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683806(US20240217988, Example 31)
Affinity DataIC50: 45.6nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM683804(US20240217988, Example 26 | (6S,8R)-6-(5-((1-(3-fl...)
Affinity DataIC50: 58.4nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM300969(US10961241, Example 36 | BDBM300970 | US10961241, ...)
Affinity DataIC50: 62nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Shenzhen Forward Pharmaceuticals Co.

US Patent
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 578nMAssay Description:1x Tris-HCl (Sigma, PHG0002) protein buffer was prepared and mixed for later use. The compound to be detected was prepared into a stock solution with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent