Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 12292
TargetV299L(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 0.190nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetV299L(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 0.510nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetY253F(Human)
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 0.510nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetY253F(Human)
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 0.530nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetABL1(Human)
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 0.610nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetE255V(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 0.610nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetY253H(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 0.930nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetQ252H(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 1.20nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetABL1(Human)
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 1.20nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetH396P(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 1.20nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetH396P(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 1.40nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetE255V(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 1.40nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetM351T(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 1.5nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetG250E(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 1.5nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetQ252H(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 1.70nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetE255K(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 2nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetE255K(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 3.40nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetY253H(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 3.60nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetG250E(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 3.70nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetM351T(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 4.5nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetF317L(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 17nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetF317I(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 47nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetF317L(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 107nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetF317I(Homo sapiens (Human))
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 114nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetT351I(Human)
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US Patent
LigandPNGBDBM693816((1S,2S)-2-fluoro-N-[3-(5-fluoro-4-methylpyridin-3-...)
Affinity DataIC50: 500nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent

TargetT351I(Human)
Enliven

US Patent
LigandPNGBDBM693815(N-[3-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-2-ox...)
Affinity DataIC50: 4.40E+3nMAssay Description:Kinase activity of ABL1 was measured using the ADP-Glo system (Promega), which measures formation of ADP using a luminescence-based method. Compounds...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
US Patent