Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 12355
LigandChemical structure of BindingDB Monomer ID 697196BDBM697196(US20240316020, Example 11 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  20nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697189BDBM697189(US20240316020, Example 4 | 1-[[2- (difluoromethoxy...)
Affinity DataEC50:  20nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697190BDBM697190(US20240316020, Example 5 | 1-[[2-(2,2- difluoropro...)
Affinity DataEC50:  20nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697192BDBM697192(US20240316020, Example 7 | 1-[[2- (cyclopropylmeth...)
Affinity DataEC50:  50nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697193BDBM697193(US20240316020, Example 8 | 1-[[2- (difluoromethoxy...)
Affinity DataEC50:  60nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697191BDBM697191(US20240316020, Example 6 | 1-[[2-(2- fluoropropoxy...)
Affinity DataEC50:  60nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697198BDBM697198(US20240316020, Example 13 | 1-[2-hydroxy-1- [2-(2,...)
Affinity DataEC50:  70nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697214BDBM697214(US20240316020, Example 29 | 1-[[2-(2,3- difluoropr...)
Affinity DataEC50:  100nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697216BDBM697216(US20240316020, Example 31 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  140nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697201BDBM697201(US20240316020, Example 16 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  150nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697197BDBM697197(US20240316020, Example 12 | 1- spiro[2.3]hexan- 5-...)
Affinity DataEC50:  170nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697195BDBM697195(US20240316020, Example 10 | 1- spiro[3.3]heptan- 2...)
Affinity DataEC50:  190nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697194BDBM697194(US20240316020, Example 9 | 1-[[2-(1,1- difluoroeth...)
Affinity DataEC50:  190nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697206BDBM697206(US20240316020, Example 21 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  210nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697206BDBM697206(US20240316020, Example 21 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  210nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697212BDBM697212(US20240316020, Example 27 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697212BDBM697212(US20240316020, Example 27 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  260nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697209BDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697209BDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697204BDBM697204(US20240316020, Example 19 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  350nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697204BDBM697204(US20240316020, Example 19 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  350nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697203BDBM697203(US20240316020, Example 18 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  410nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697211BDBM697211(US20240316020, Example 26 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  440nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697215BDBM697215(US20240316020, Example 30 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  450nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697188BDBM697188(US20240316020, Example 3 | 1-[[2- (difluoromethoxy...)
Affinity DataEC50:  500nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697213BDBM697213(US20240316020, Example 28 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  500nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697213BDBM697213(US20240316020, Example 28 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  500nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697217BDBM697217(US20240316020, Example 32 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  550nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697210BDBM697210(US20240316020, Example 25 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  740nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697210BDBM697210(US20240316020, Example 25 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  740nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697207BDBM697207(US20240316020, Example 22 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  1.44E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697208BDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  1.94E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697208BDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  1.94E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697200BDBM697200(US20240316020, Example 15 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  3.10E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697186BDBM697186(US20240316020, Example 1 | 1-(1- oxaspiro[4.4] non...)
Affinity DataEC50:  3.63E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697205BDBM697205(US20240316020, Example 20 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  8.43E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697187BDBM697187(US20240316020, Example 2 | 1-(6- oxaspiro[4.5] dec...)
Affinity DataEC50:  8.49E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697213BDBM697213(US20240316020, Example 28 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697212BDBM697212(US20240316020, Example 27 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697210BDBM697210(US20240316020, Example 25 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697209BDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697208BDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697206BDBM697206(US20240316020, Example 21 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697204BDBM697204(US20240316020, Example 19 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 697199BDBM697199(US20240316020, Example 14 | BDBM697202 | 1-[[2- (d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent