Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 12365
TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698769BDBM698769(US20240317745, Compound 47)
Affinity DataKi:  0.740nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.04nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698774BDBM698774(US20240317745, Reference Compound 1)
Affinity DataKi:  6.17nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698767BDBM698767(US20240317745, Compound 43)
Affinity DataKi:  7.97nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698772BDBM698772(US20240317745, Compound 77)
Affinity DataKi:  14.9nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698768BDBM698768(US20240317745, Compound 44)
Affinity DataKi:  19nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698766BDBM698766(US20240317745, Compound 41)
Affinity DataKi:  34nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698770BDBM698770(US20240317745, Compound 65)
Affinity DataKi:  39.6nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698762BDBM698762(US20240317745, Compound 20)
Affinity DataKi:  48.9nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698760BDBM698760(US20240317745, Compound 1)
Affinity DataKi:  80.3nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698771BDBM698771(US20240317745, Compound 74)
Affinity DataKi:  84.4nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698761BDBM698761(US20240317745, Compound 19)
Affinity DataKi:  172nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698765BDBM698765(US20240317745, Compound 40)
Affinity DataKi:  190nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698763BDBM698763(US20240317745, Compound 37)
Affinity DataKi:  308nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698775BDBM698775(US20240317745, Reference Compound 2)
Affinity DataKi:  313nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698764BDBM698764(US20240317745, Compound 38)
Affinity DataKi:  378nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandChemical structure of BindingDB Monomer ID 698773BDBM698773(US20240317745, Compound 88)
Affinity DataKi:  959nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent