Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 12374
TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699087BDBM699087(4-(8-((2-fluoro-5-(trifluoromethyl)benzoyl)-D- val...)
Affinity DataIC50: 1.10nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699076BDBM699076(2-fluoro-N-((2R)-1-(4-(4-methoxyphenyl)-2- methyl-...)
Affinity DataIC50: 1.70nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699090BDBM699090(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-4-(p- tolyl)...)
Affinity DataIC50: 2.20nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699084BDBM699084(N-((2R)-1-(4-(4-fluorophenyl)-2-methyl-2,8- diazas...)
Affinity DataIC50: 3.40nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699100BDBM699100(2-fluoro-N-((2R)-3-methyl-1-oxo-1-(10-oxo-7- pheny...)
Affinity DataIC50: 3.5nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699072BDBM699072(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-1-oxo-4- phe...)
Affinity DataIC50: 3.80nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699056BDBM699056(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-1-oxo-4- phe...)
Affinity DataIC50: 4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699094BDBM699094(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- methyl-2...)
Affinity DataIC50: 4.10nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699093BDBM699093(N-((1R)-1-cyclohexyl-2-(4-(4-fluorophenyl)-2- meth...)
Affinity DataIC50: 4.40nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699108BDBM699108(2-fluoro-N-((2R)-1-(7-(4-fluorophenyl)-9- methyl-3...)
Affinity DataIC50: 5.10nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699101BDBM699101(2-fluoro-N-((2R)-1-(7-(4-fluorophenyl)-10-oxo- 3,9...)
Affinity DataIC50: 6.5nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699061BDBM699061(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-4- phenyl-2,...)
Affinity DataIC50: 6.60nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699082BDBM699082(2-fluoro-N-((2R)-1-(4-(4-methoxyphenyl)-2- methyl-...)
Affinity DataIC50: 6.80nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699065BDBM699065(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- methyl-1...)
Affinity DataIC50: 6.90nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699063BDBM699063(N-((2R)-1-(4-(1H-indazol-5-yl)-2-methyl-2,8- diaza...)
Affinity DataIC50: 6.90nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699098BDBM699098(N-((2R)-1-(4-(4-fluorophenyl)-2-methyl-2,8- diazas...)
Affinity DataIC50: 6.90nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699079BDBM699079(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- methyl-2...)
Affinity DataIC50: 7.10nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699103BDBM699103(2-fluoro-N-((2R)-1-(7-(4-fluorophenyl)-9- methyl-1...)
Affinity DataIC50: 7.5nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699089BDBM699089(2-fluoro-N-((R)-1-((S)-4-(4-fluorophenyl)-2- methy...)
Affinity DataIC50: 7.80nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699083BDBM699083(2-fluoro-N-((2R)-1-(4-(4-methoxyphenyl)-2- methyl-...)
Affinity DataIC50: 9.30nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699107BDBM699107(2-fluoro-N-((2R)-3-methyl-1-(9-methyl-7- phenyl-3,...)
Affinity DataIC50: 9.90nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699071BDBM699071(2-fluoro-5-methyl-N-((2R)-3-methyl-1-(2- methyl-1-...)
Affinity DataIC50: 10.1nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699099BDBM699099(4-methyl-N-((2R)-3-methyl-1-(2-methyl-4- (pyridin-...)
Affinity DataIC50: 10.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699102BDBM699102(2-fluoro-N-((2R)-3-methyl-1-(9-methyl-10-oxo- 7-ph...)
Affinity DataIC50: 11.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699092BDBM699092(2-fluoro-N-((1R)-2-(4-(4-fluorophenyl)-2- methyl-2...)
Affinity DataIC50: 11.5nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699066BDBM699066(N-((2R)-1-(2-ethyl-4-(4-fluorophenyl)-1-oxo-2,8- d...)
Affinity DataIC50: 11.7nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699088BDBM699088(2-fluoro-N-((R)-1-((R)-4-(4-fluorophenyl)-2- methy...)
Affinity DataIC50: 12nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699105BDBM699105(2-fluoro-N-((2S)-3-methyl-1-(9-methyl-10-oxo- 7-ph...)
Affinity DataIC50: 12nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699058BDBM699058(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-1-oxo-4- (py...)
Affinity DataIC50: 13.3nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699062BDBM699062(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-4- (pyridin-...)
Affinity DataIC50: 13.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699106BDBM699106(N-((2R)-3-methyl-1-(9-methyl-10-oxo-7-phenyl- 3,9-...)
Affinity DataIC50: 15.9nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699070BDBM699070(N-((2R)-3-methyl-1-(2-methyl-1-oxo-4-phenyl- 2,8-d...)
Affinity DataIC50: 16.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699104BDBM699104(N-((2R)-1-(9-ethyl-7-(4-fluorophenyl)-10-oxo- 3,9-...)
Affinity DataIC50: 17.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699057BDBM699057(2-fluoro-N-((2R)-3-methyl-1-oxo-1-(1-oxo-4- phenyl...)
Affinity DataIC50: 19.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699064BDBM699064(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-1-oxo- 2,8-...)
Affinity DataIC50: 22.6nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699067BDBM699067(2-fluoro-5-methoxy-N-((2R)-3-methyl-1-(2- methyl-1...)
Affinity DataIC50: 25.6nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699073BDBM699073(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- isopropy...)
Affinity DataIC50: 34.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699091BDBM699091(N-((2R)-1-(4-(3,5-dimethylphenyl)-2-methyl-2,8- di...)
Affinity DataIC50: 40.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699080BDBM699080(2-fluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- isopropy...)
Affinity DataIC50: 44.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699095BDBM699095(2,5-difluoro-N-((2R)-1-(4-(4-fluorophenyl)-2- meth...)
Affinity DataIC50: 47.3nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699097BDBM699097(N-((2R)-1-(4-(4-fluorophenyl)-2-methyl-2,8- diazas...)
Affinity DataIC50: 48.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699068BDBM699068((R)-2-fluoro-N-(3-methyl-1-(2-methyl-1-oxo-4- phen...)
Affinity DataIC50: 55.6nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699059BDBM699059(2-fluoro-N-((2R)-3-methyl-1-oxo-1-(1-oxo-4- (pyrid...)
Affinity DataIC50: 56.2nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699060BDBM699060(N-((2R)-1-(4-(1H-indazol-5-yl)-2-methyl-1-oxo- 2,8...)
Affinity DataIC50: 58.9nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699085BDBM699085(methyl 8-((2-fluoro-5-(trifluoromethyl)benzoyl)- D...)
Affinity DataIC50: 59.7nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699069BDBM699069(2-fluoro-N-((2R)-3-methyl-1-(2-methyl-1-oxo-4- phe...)
Affinity DataIC50: 66.8nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699055BDBM699055(N-((2R)-1-(2-(2-aminoethyl)-1,3-dioxo-4-phenyl- 2,...)
Affinity DataIC50: 69.8nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699074BDBM699074(N-((2R)-1-(2-(cyclopropylmethyl)-4-(4- fluoropheny...)
Affinity DataIC50: 73.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699077BDBM699077(2-fluoro-N-((2R)-3-methyl-1-oxo-1-(2-oxo-4- phenyl...)
Affinity DataIC50: 74.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetAutotaxin(Rat)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 699081BDBM699081(N-((2R)-1-(2-(cyclopropylmethyl)-4-(4- fluoropheny...)
Affinity DataIC50: 84.4nMAssay Description:The biochemical reaction consisted of 50 mM Tris (pH 8.0), 3 mM KCl, 1 mM CaCl2, 1 mM Mg Cl2, 0.14 mM NaCl and 0.1% bovine serum albumin, which was s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

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