Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12420
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701602(US20240352053, Compound Control Example 1)
Affinity DataIC50: 0.200nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701603(US20240352053, Compound Formula I)
Affinity DataIC50: 0.300nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701602(US20240352053, Compound Control Example 1)
Affinity DataIC50: 5.10nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent

TargetInsulin-like growth factor 1 receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701602(US20240352053, Compound Control Example 1)
Affinity DataIC50: 9.5nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701603(US20240352053, Compound Formula I)
Affinity DataIC50: 20.2nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent

TargetInsulin-like growth factor 1 receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM701603(US20240352053, Compound Formula I)
Affinity DataIC50: 195nMAssay Description:Mobility shift assays were performed to determine the compound's inhibitory activity against EGFR delta19del/T790M/C797S, EGFR WT, and IGF1R kinases....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
US Patent