Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 12431
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702016(US20240360091, Compound (10165)R)
Affinity DataIC50: 19nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702032(US20240360091, Compound (10272)R)
Affinity DataIC50: 22nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702030(US20240360091, Compound (NP10679)R)
Affinity DataIC50: 23nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702038(US20240360091, Compound (10245)R)
Affinity DataIC50: 25nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9 | US20240360091, Co...)
Affinity DataIC50: 29nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702014(US20240360091, Compound (10166)R)
Affinity DataIC50: 30nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702031(US20240360091, Compound (10294)S)
Affinity DataIC50: 30nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702011(US20240360091, Compound (93-108)S)
Affinity DataIC50: 31nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702023(US20240360091, Compound (10224)R)
Affinity DataIC50: 34nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702037(US20240360091, Compound (10171)S)
Affinity DataIC50: 46nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168619(US9079852, Table F, Compound 4 | US20240360091, Co...)
Affinity DataIC50: 46nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702012(US20240360091, Compound (10233)R)
Affinity DataIC50: 47nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702036(US20240360091, Compound (10244)R)
Affinity DataIC50: 47nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702025(US20240360091, Compound (10052)R)
Affinity DataIC50: 50nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702020(US20240360091, Compound (10222)R)
Affinity DataIC50: 52nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702016(US20240360091, Compound (10165)R)
Affinity DataIC50: 60nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702034(US20240360091, Compound (10243)R)
Affinity DataIC50: 71nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702035(US20240360091, Compound (10040)S)
Affinity DataIC50: 74nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702024(US20240360091, Compound (10030)S)
Affinity DataIC50: 87nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702019(US20240360091, Compound (10189)S)
Affinity DataIC50: 94nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702018(US20240360091, Compound (10225)R)
Affinity DataIC50: 97nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702013(US20240360091, Compound (10131)S)
Affinity DataIC50: 103nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702029(US20240360091, Compound (NP10309)S)
Affinity DataIC50: 111nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702032(US20240360091, Compound (10272)R)
Affinity DataIC50: 128nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702021(US20240360091, Compound (10215)S)
Affinity DataIC50: 130nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702014(US20240360091, Compound (10166)R)
Affinity DataIC50: 132nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702030(US20240360091, Compound (NP10679)R)
Affinity DataIC50: 142nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702040(US20240360091, Compound (10247)R)
Affinity DataIC50: 144nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702023(US20240360091, Compound (10224)R)
Affinity DataIC50: 171nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702020(US20240360091, Compound (10222)R)
Affinity DataIC50: 183nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702031(US20240360091, Compound (10294)S)
Affinity DataIC50: 209nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702033(US20240360091, Compound (10039)S)
Affinity DataIC50: 217nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702017(US20240360091, Compound (10214)S)
Affinity DataIC50: 221nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702035(US20240360091, Compound (10040)S)
Affinity DataIC50: 260nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702025(US20240360091, Compound (10052)R)
Affinity DataIC50: 272nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702012(US20240360091, Compound (10233)R)
Affinity DataIC50: 294nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702036(US20240360091, Compound (10244)R)
Affinity DataIC50: 305nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702037(US20240360091, Compound (10171)S)
Affinity DataIC50: 316nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702039(US20240360091, Compound (10082)S)
Affinity DataIC50: 356nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168624(US9079852, Table F, Compound 9 | US20240360091, Co...)
Affinity DataIC50: 370nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702038(US20240360091, Compound (10245)R)
Affinity DataIC50: 385nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702026(US20240360091, Compound (10235)S)
Affinity DataIC50: 398nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM168619(US9079852, Table F, Compound 4 | US20240360091, Co...)
Affinity DataIC50: 452nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702033(US20240360091, Compound (10039)S)
Affinity DataIC50: 476nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702018(US20240360091, Compound (10225)R)
Affinity DataIC50: 527nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702027(US20240360091, Compound (10249)R)
Affinity DataIC50: 549nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702011(US20240360091, Compound (93-108)S)
Affinity DataIC50: 558nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702034(US20240360091, Compound (10243)R)
Affinity DataIC50: 574nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702040(US20240360091, Compound (10247)R)
Affinity DataIC50: 675nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM702029(US20240360091, Compound (NP10309)S)
Affinity DataIC50: 717nMAssay Description:The GluN2B potency and pH dependence of NP10679, NP10309, and other compounds in Tables 1 and 2 were evaluated on human GluN1-la/GluN2B receptors (he...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

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