Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 12438
TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702899((3S)-3-(4-((4-((3-((2- methoxyethoxy)methyl) morph...)
Affinity DataKd: <100nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702905((S)-3-(6-(2-methoxyethoxy)-4- ((4- (morpholinometh...)
Affinity DataKd: <100nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702906((S)-3-(4-((3-((2- methoxyethyl)amino)-4- (morpholi...)
Affinity DataKd: <100nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702903(1-(4-(((2-((S)-2,6- dioxopiperidin-3-yl)-1- oxoiso...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702904((S)-3-(4-((4-((4-((2- methoxyethoxy)methyl)piperid...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702901(1-(4-(((2-((S)-2,6- dioxopiperidin-3-yl)-1- oxoiso...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702902((S)-1-(4-(((2-(2,6- dioxopiperidin-3-yl)-1- oxoiso...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702900((3S)-3-(4-((4-((3-(((2- methoxyethyl)amino)methyl)...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702907((S)-3-(4-((2-((2- methoxyethyl)amino)-4- (morpholi...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM702908((S)-5-(((2-(2,6-dioxopiperidin- 3-yl)-1-oxoisoindo...)
Affinity DataKd:  550nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataKd: >1.00E+3nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Oerth Bio

US Patent
LigandPNGBDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataKd: >1.00E+3nMAssay Description:The binding affinity of the described test compounds was determined using RED-tris-NTA His-tag labeled Cereblon ligand binding domain. The labeling o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent