Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 12568
TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623129(CHEMBL5419365 | US20250000864, Compound 7)
Affinity DataIC50: 0.220nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50347982(CHEMBL1800159 | US20250000864, Compound Relugolix)
Affinity DataIC50: 0.25nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623120(CHEMBL5434324 | US20250000864, Compound 3)
Affinity DataIC50: 0.260nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623121(CHEMBL5427278 | US20250000864, Compound 5)
Affinity DataIC50: 0.380nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623126(CHEMBL5413078 | US20250000864, Compound 6)
Affinity DataIC50: 0.550nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM710400(US20250000864, Compound 1)
Affinity DataIC50: 0.570nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM710401(US20250000864, Compound 2)
Affinity DataIC50: 0.640nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM710402(US20250000864, Compound 2A)
Affinity DataIC50: 0.870nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent