Compile Data Set for Download or QSAR
Report error Found 614 Enz. Inhib. hit(s) with all data for entry = 12607
LigandPNGBDBM713227((Method 2): 1-((R)-3-((7-(8-chloro-3-hydroxynaphth...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713235((Method 4):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713229((Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713230((Method 4): 1-((R)-3-((7-(8-chloro-3-hydroxynaphth...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713211((Method 1): 1-((R)-3-((7-(8-chloro-7-fluoronaphtha...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713210((Method 8): (E)-1-((R)-3-((7-(8-chloro-7-fluoronap...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713206((Method 1): (E)-1-((R)-3-((7-(8-chloro-7-fluoronap...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713219((Method 1):(E)-1-((R)-3-((7-(8-chloro-7-fluoronaph...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713217((Method 1): (E)-1-((R)-3-((7-(8-chloronaphthalen-1...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713218((Method 1): (R,E)-1-(3-((7-(8-chloronaphthalen-1-y...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713216((Method 1): (E)-1-(3-(((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713260((Method 2):(R,E)-1-(3-((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713262((Method 4):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713269((Method 2):(R,E)-1-(3-((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713270((Method 11):(E)-1-((3S,4S)-3-((7-(8-chloronaphthal...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713265((Method 4):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713263((Method 4):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713244((Method 2-Master): 1-((R)-3-((8-fluoro-2-(((2R,7aS...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713245((Method 1):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713243((Method 1):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713239((Method 4):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713240((Method 1):(R,E)-1-(3-((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713237((Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713253((Method 2):(R,E)-1-(3-((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713251((Method 2):(R,E)-1-(3-((7-(8-chloronaphthalen-1-yl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713248((Method 4):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713249((Method 1):(E)-1-(3-(((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713246((Method 1):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713288((Method 11-Master):(E)-1-((R)-3-((7-(8-ethynyl-7-f...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713289((Method 1):(E)-4-(dimethylamino)-1-((R)-3-((7-(8-e...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713303((Method 1):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713299((Method 8):(E)-1-((R)-3-((7-(8-chloro-7-fluoronaph...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713296((Method 1):(E)-1-((R)-3-((7-(8-chloronaphthalen-1-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713279((Method 11):(E)-1-((R)-3-((7-(7,8-difluoronaphthal...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713273((Method 7): 1-((R)-3-((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713274((Method 1):1-((R)-3-((7-(8-ethynyl-7-fluoronaphtha...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713287((Method 11):(E)-1-((3S,4S)-3-((7-(7, 8-difluoronap...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713325((Method 13): 4-(azetidin-1-yl)-1-((R)-3-((7-(8-chl...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713595(US20250019387, Table 1a.323)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713324((Method 12-master):(E)-1-((R)-3-((7-(8-chloronapht...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713336((Method 7): 1-((R)-3-((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713334((Method 11):(E)-1-((3S,4S)-3-((7-(8-chloro-7-fluor...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713608(US20250019387, Table 1a.335)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713331((Method 7): 1-((R)-3-((7-(8-chloronaphthalen-1-yl)...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713329((Method 2): 1-((R)-3-((7-(8-ethyl-7-fluoro-3-hydro...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713311((Method 8):(E)-1-((R)-3-((7-(8-chloro-7-fluoronaph...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713309((Method 8):(E)-1-(3-(((7-(8-chloro-7-fluoronaphtha...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713310((Method 8):(E)-1-(3-(((7-(8-chloro-7-fluoronaphtha...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713320((Method 2):(R,E)-1-(3-((7-(7,8-difluoronaphthalen-...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

LigandPNGBDBM713318((Method 2):(E)-1-(3-(((7-(8-chloro-7-fluoronaphtha...)
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50s for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/27/2025
Entry Details
US Patent

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