Compile Data Set for Download or QSAR
Report error Found 490 Enz. Inhib. hit(s) with all data for entry = 12619
TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715306BDBM715306(US20250026748, Compound 470)
Affinity DataIC50: 0.0490nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715294BDBM715294(US20250026748, Compound 458)
Affinity DataIC50: 0.100nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715041BDBM715041(US20250026748, Compound 205)
Affinity DataIC50: 0.160nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714882BDBM714882(US20250026748, Compound 46)
Affinity DataIC50: 0.200nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715089BDBM715089(US20250026748, Compound 253)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715101BDBM715101(US20250026748, Compound 265)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715099BDBM715099(US20250026748, Compound 263)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715100BDBM715100(US20250026748, Compound 264)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715080BDBM715080(US20250026748, Compound 244)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715073BDBM715073(US20250026748, Compound 237)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715088BDBM715088(US20250026748, Compound 252)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715084BDBM715084(US20250026748, Compound 248)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715081BDBM715081(US20250026748, Compound 245)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714871BDBM714871(US20250026748, Compound 35)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714869BDBM714869(US20250026748, Compound 33)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715124BDBM715124(US20250026748, Compound 288)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714879BDBM714879(US20250026748, Compound 43)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714877BDBM714877(US20250026748, Compound 41)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714876BDBM714876(US20250026748, Compound 40)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715129BDBM715129(US20250026748, Compound 293)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715112BDBM715112(US20250026748, Compound 276)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715119BDBM715119(US20250026748, Compound 283)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715116BDBM715116(US20250026748, Compound 280)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715114BDBM715114(US20250026748, Compound 278)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714903BDBM714903(US20250026748, Compound 67)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715156BDBM715156(US20250026748, Compound 320)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714897BDBM714897(US20250026748, Compound 61)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715153BDBM715153(US20250026748, Compound 317)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714911BDBM714911(US20250026748, Compound 75)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714912BDBM714912(US20250026748, Compound 76)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715161BDBM715161(US20250026748, Compound 325)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715143BDBM715143(US20250026748, Compound 307)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715137BDBM715137(US20250026748, Compound 301)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714891BDBM714891(US20250026748, Compound 55)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714892BDBM714892(US20250026748, Compound 56)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714890BDBM714890(US20250026748, Compound 54)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714936BDBM714936(US20250026748, Compound 100)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715192BDBM715192(US20250026748, Compound 356)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714931BDBM714931(US20250026748, Compound 95)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715187BDBM715187(US20250026748, Compound 351)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715188BDBM715188(US20250026748, Compound 352)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715185BDBM715185(US20250026748, Compound 349)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714930BDBM714930(US20250026748, Compound 94)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715186BDBM715186(US20250026748, Compound 350)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715199BDBM715199(US20250026748, Compound 363)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714944BDBM714944(US20250026748, Compound 108)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714942BDBM714942(US20250026748, Compound 106)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714937BDBM714937(US20250026748, Compound 101)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715193BDBM715193(US20250026748, Compound 357)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 715194BDBM715194(US20250026748, Compound 358)
Affinity DataIC50: 0.25nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

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