Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 12629
TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716250(US20250032476, Compound PS75)
Affinity DataKi:  8.20nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM50085683(4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole ...)
Affinity DataKi:  10nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716248(US20250032476, Compound 4622)
Affinity DataKi:  12nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716249(US20250032476, Compound 7075)
Affinity DataKi:  37nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716245(US20250032476, Compound 9087)
Affinity DataKi:  51nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM50225285(CHEBI:3757 | Catapres | Catapres-Tts-1 | Catapres-...)
Affinity DataKi:  84nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716246(US20250032476, Compound 2998)
Affinity DataKi:  180nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM716247(US20250032476, Compound 0172)
Affinity DataKi:  260nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetAlpha-2A adrenergic receptor(Human)
University Of California

US Patent
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKi:  4.10E+3nMAssay Description:Competition binding with α2AR subtypes were performed by incubating membranes in buffer A (50 mM TRIS at pH 7.4) at final protein concentrations of 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent